Methods Of Use Of Cas12L/CasLambda In Plants

Tech ID: 32524 / UC Case 2022-026-0

Patent Status

Patent Pending

Brief Description


UC researchers have discovered a novel use of proteins denoted CasLamda/Cas12L

within the Type V CRISPR Cas superfamily distantly related to CasX, CasY and other published type V sequences.  These CasLamda/Cas12L proteins utilize a guide RNA to perform RNA-directed cleavage of DNA.  The researchers have developed compounds and structures for use in in editing plant cells.

Suggested uses


  • Targeted genome editing of plant cells
  • Targeting of proteins bound to CasLamda/Cas12L to a specific locus of a genome

 


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Inventors

  • Doudna, Jennifer A.

Other Information

Keywords

CRISPR, Cas12L, CasLambda

Categorized As

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