Transposon Vector for Vertebrate & Invertebrate Genetic Manipulation

Tech ID: 25287 / UC Case 2012-608-0

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 9,790,477 10/17/2017 2012-608


Photo by NIH

Brief Description


Therapeutic delivery of genes is a rapidly evolving technique used to treat or prevent a disease at the root of the problem. The global transgenic market is currently $24B, growing at an annual projected rate of 10%. Currently, a variation of this technique is widely used on animals and crops for production of desirable proteins, but this is a heavily infiltrated market. Thus, entering the gene therapy segment is more promising and would enhance the growth of this industry.


Brief Description:

UCR Researchers have identified a novel transposon from Aedes aegypti mosquitoes. This mobile DNA sequence can insert itself into various functional genes to either cause or reverse mutations. They have successfully developed a transposon vector system that can be used in both unicellular & multicellular organisms, which can offer notable insight to improve current transgenic technologies as well as methods of gene therapy.


  • Various types of vectors – introduce transposons to targeted areas in different organisms
  • Successful creation of transgenic animals – genetic transformations in vertebrate and invertebrate cells


  • Research tool for transgenic technology – produce therapeutic proteins or disrupt gene function, e.g. transform mosquito genes to minimize spread of arboviral disease
  • Gene therapy – alter genes to treat or prevent genetic problems


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Other Information


transposon, transposable elements, transgenic technology, genetic tool, gene therapy, genetic manipulation, mobile DNA, transposon vector system

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