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AAV-Based Gene Therapy for Glioblastoma Treatment Using Interferon Cytokines
Brief description not available
Enhancing Cancer Immunotherapy with Modified Adaptor Protein and CAR-NK Cell Technology
Next-Generation Monoclonal Antibody Therapy Targeting High-Risk Tumors
Affinity-Matured Anti-Cd72 Nanobodies For Next-Generation CAR-T Immunotherapies
Vaccines Using Macrophage Suppression
Researchers at the University of California, Davis have developed a technology that introduces vaccines that express macrophage-suppressing molecules to significantly enhance inflammatory T-cell functions for improved immune responses.
Lung-Targeted Cell-Based Therapies for Inflammatory Disease and Cancer
Innovative T Cell Gene Editing System for Enhanced Cancer Immunotherapy
Dual Modality Radionuclide-Antibody Drug Conjugate for Advanced Prostate Cancer and Multiple Myeloma
Targeting Tumor-Associated Macrophages to Overcome Immunotherapy Resistance
Dual-Antigen Targeting CAR-T Therapy for Acute Myeloid Leukemia (AML)
A Novel In Vivo Genome-Wide CRISPR Screening Platform for Enhancing T Cell Immunotherapies in Solid Tumors
A Novel Approach to Overcome T Cell Exhaustion for Enhanced Anti-Tumor Activity
Macrophage Targeting Peptides - Peptide Sequences that are Specific to M1 And M2 Macrophages for Application in Molecular Imaging and Therapy
Researchers at the University of California, Davis have developed isolated peptides that selectively bind M1 and M2 macrophages to enable precise diagnosis and targeted treatment of macrophage-associated diseases, including cancer.
Cationic Silyl-Lipids for Enhanced Delivery of Anti-viral Therapeutics
Researchers at the University of California, Davis have developed an advancement in the field of healthcare technology, specifically in the development and application of silyl lipids for RNA vaccines.
Silyl-lipid N-acyl L-homoserine Lactones (AHLs) as Quorum Sensing Molecules (for Biofilms)
Researchers at the University of California, Davis have developed a potential therapeutic strategy aiming at disrupting intercellular communication of pathogens using quorum sensing molecules and silicon-based pharmacophores.
Silyl-lipid Cannabinoids with Enhanced Biological Activity
Researchers at the University of California, Davis have developed a therapeutic use of cannabinoids for the treatment of Neurodegenerative Disorders (NDDs).
Nanoplatform for Cancer Therapy
Researchers at the University of California, Davis have developed a nanoparticle system combining photothermal therapy and chemotherapy for enhanced cancer treatment.
Intranasal Delivery of Allopregnanolone
Researchers at the University of California, Davis have developed non-invasive methods for intranasally delivering the drug allopregnanolone.
Inhibitor for Preventing the Onset of Neurodevelopmental Disorders
Researchers at the University of California, Davis and the Chiba University Center for Forensic Mental Health in Japan have collaborated to develop an enzyme inhibitor that prevents the onset of neurodevelopmental disorders.
Targeting Cancer Cachexia with Soluble Epoxide Hydrolase Inhibitors
Researchers at the University of California, Davis have developed a therapeutic approach to prevent and treat cancer cachexia by inhibiting soluble epoxide hydrolase, promoting resolution of systemic inflammation, mitigating muscle wasting, and improving survival outcomes in preclinical models without inducing toxicity or immunosuppression.
Hydrogelated Cells for Regenerative Medicine Applications
Researchers at the University of California, Davis have developed a technology that introduces an approach to creating semi-living, non-replicating cellular systems for advanced therapeutic applications.
Site-specific Chemical Ligation of Native Human Serum Albumin as a Carrier for Drugs
Researchers at the University of California, Davis, have developed a method to prepare chemically well-defined HSA-drug conjugates, such that ligation can occur in vitro or in vivo under physiological condition.
Modified SYNGAP1 Protein Expressed in a Lentiviral Vector for the Treatment of Patients with SYNGAP1-related Intellectual Disability
Researchers at the University of California, Davis have developed a novel stem cell gene therapy approach utilizing a modified SYNGAP1 protein to treat Synaptic Ras GTPase Activating Protein 1-related intellectual disability (SRID).
Novel Anti-HLA-Pan-DP CAR-T cells for Targeted Cancer Immunotherapy
Targeted Immunotherapy for Multiple Myeloma: Novel Mutant CCL27 Binders Targeting CCR10