A revolutionary optical technology designed to restore peripheral vision in patients with eye diseases through the integration of optical metasurfaces on eyewear.

A groundbreaking technology that efficiently transforms dilute CO2 streams into methane using sorbent materials and electrocatalysis.

Brief description not available

Brief description not available

With the rise of biotechnology, synthetic biology, and metabolic engineering, enzymes can be used as tools to catalyze a desired chemical reaction, even those that are non-natural. As enzymes often act on an array of structurally related compounds, they are often probed for activity on substrates other than their natural one to form a structure activity relationship (SAR). Additionally, when searching for the best performing enzyme, it is often desirable to either apply protein engineering to create new enzymes with a desired characteristic or screen several homologs. Though there are many assays for monitoring enzymatic reactions, many are laborious and low-throughput and therefore severely limit the space that can be experimentally mined. As gene synthesis costs continue to decrease, the ability to perform such assays becomes the dominant bottleneck in mining efforts.  A high throughput assay for enzyme activity, which matches the scalability of new DNA synthesis methods would constitute a significant advance in the art.UC Berkeley researchers have developed assays and methods to improve throughput and cost of enzyme characterization that matches the scalability of new DNA synthesis.  The assay developed is a DNA-linked enzyme-coupled assay which can monitor enzyme reactions in a manner amenable to multiplex gene synthesis and can be linked to multiplex readout in droplets and deep sequencing instrumentation.

Supercapacitors are electrochemical energy-storage devices that store charge by reversible adsorption of ions onto high-surface area, porous materials (known as “electric double layer capacitors”) or reversible surface reduction-oxidation (redox) reactions (known as “pseudo-capacitors”). With their high power density and long cycle stability, supercapacitors are well-suited to complement or replace batteries in a wide range of applications, including transportation, renewable energy, and portable electronics. High-performance supercapacitors are characterized by high specific capacitance, good stability over repeated cycling, and low series resistance. UC Berkeley researchers and others developed a method to a fabricate high surface area, high performance supercapacitor.

According to the American Heart Association, an estimated 82.4 million American live with one or more types of cardiovascular disease. Annually, about 2.7% of Americans suffer a myocardial infarction (heart attack). Patients who survive acute myocardial infarction continue to suffer from loss of cardiomyocytes, cardiac scar formation, ventricular remodeling, and in most cases, eventual heart failure. UC Berkeley researchers have discovered that a small population of cells in the adult heart have the capacity to self-renew and to differentiate into one or more cell types of the heart. 

Skin rejuvenation methods aim to remove damaged tissue and stimulate new growth of healthy collagen, skin cells, and elastin fibers. Currently the most popular therapies include percutaneous collagen induction (PCI) and laser therapies. PCI has a low side effect profile, but has very limited clinical data. Although laser treatments have good clinical data, they also have a poor side effect profile with many patients experiencing prolonged erythema, scaring, and dyspigmentation. The market needs a technology with fewer side effects, a better safety profile, lower cost, and one that is convenient enough to be sold over the counter.UC Berkeley researchers have develeoped systems and methods for delivering electric fields in a manner that controls or promotes tissue repair, enhancement, and disinfection.