Isolation and Preservation of Extracellular Vesicles with EXO-PEG-TR
Tech ID: 33978 / UC Case 2024-9AM-0
Brief Description
A
groundbreaking method for the efficient isolation and preservation of
high-purity small extracellular vesicles (sEVs - exosomes) from biofluids using
a novel EXO-PEG-TR reagent.
Full Description
This
technology introduces a novel approach to the isolation and preservation of sEVs
including exosomes, from various biofluids. Utilizing a newly developed
reagent, EXO-PEG-TR, this method allows for the separation of high-purity sEVs
without the need for complex equipment. Designed to overcome the limitations of
current sEV isolation techniques, such as ultracentrifugation and
precipitation, EXO-PEG-TR simplifies the process, ensuring high yield and
quality of sEVs (exosomes) for further diagnostic and therapeutic applications.
Suggested uses
- Diagnostic and therapeutic applications involving small extracellular vesicles.
- Research on intercellular communication and transfer of biological cargo.
- Mapping of exosome genomics, transcriptomics, proteomics, lipidomics, and metabolomics.
- Clinical scalability of precision diagnostics.
Advantages
- High efficiency and purity isolation of extracellular vesicles.
- Minimal equipment requirement, facilitating easier clinical scalability.
- Preservation of exosome quality and quantity during storage.
- Applicable to a wide range of biofluids and cell culture media.
- Supports downstream "omics" and subpopulation studies.
- Timesaving with a simple three-step isolation
process.
Patent Status
Patent Pending