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A Wearable Platform for In-Situ Analysis of Hormones
UCLA researchers in the Department of Electrical and Computer Engineering have developed a highly sensitive, wearable hormone monitoring platform.
Ultra-Low Cost, Transferrable and Thermally Stable Sensor Array Patterned on Conductive Substrate for Biofluid Analysis
UCLA researchers from the Department of Electrical Engineering have invented a novel biosensor array that is ultra-low cost and thermally stable. It prolongs the lifetime of electrode modules of sensor products and allows for extended sensing operation in uncontrolled environments.
Wearable Monitor of Attentional Integrity and Mental Strain
UCLA researchers in the Department of Psychiatry & Biobehavioral Sciences have developed a novel brain monitoring device that can be worn inconspicuously.
Titanium Implants with Novel Roughness
UCLA researchers in the School of Dentistry at the Weintraub Center for Reconstructive Biology have developed a novel titanium implant with hierarchical multi-scale roughness to promote bone growth.
In-Situ Sweat Rate Monitoring For Normalization Of Sweat Analyte Concentrations
UCLA researchers in the Department of Electrical Engineering have developed a method of in-situ sweat rate monitoring, which can be integrated into wearable consumer electronics for physiological analyses.
Multiplexed Sweat Extraction And Sensing Wearable Interface For Normalized And Periodic Analysis
UCLA researchers from the Department of Electrical Engineering have developed a novel sweat induction and sensing platform to achieve personalized physiological monitoring non-invasively.
Novel Adjustable Caliber Catheter System
UCLA researchers in the Department of Radiological Sciences have designed a new adjustable catheter system for use in embolectomy or thrombectomy procedures.
Stamping-based Method for Microwell Production and Cell Aggregate Formation
Researchers at the University of California, Davis have developed a 3-D printed stamping system (the “Aggrestamp”) with the capability for in-situ production of microwells that facilitate cell aggregate formation.
Milk Fat Globules As A Universal Delivery System
Researchers at the University of California, Davis have developed methods that utilize molecules encapsulated in milk fat globules and plant oleosomes to deliver bioactive compounds for a variety of applications.
Biomimetic Conductive Hydrogels
UCLA researchers in the Department of Bioengineering have developed a novel electrically conductive scaffold system with a hyaluronic acid (HA)-based hydrogel for biomimetic research to treat spinal cord and other central nervous system (CNS) injuries.
Systems and Methods for Monodisperse Drop Generation and Use
UCLA researchers in the Department of Bioengineering have developed systems and methods to produce single particle, monodisperse droplets for use in digital assays, targeted drug delivery, and theranostics.
Neural Modulation Of Autonomic Nervous System To Alter Memory And Plasticity Of The Autonomic Network
Researchers at UCLA from the Departments of Medicine and Bioengineering have created a device that modulates the autonomic nervous system to treat heart conditions like arrhythmias.
Continuous, Quantitative, Selective, Non-Enzymatic Glucose Monitoring Using Conductimetric Analysis
A new molecule that enables glucose monitoring using measurements of solution conductivity.
Predicting Cefixime Susceptiblity Using Molecular Genotyping
UCLA researchers in the David Geffen School of Medicine have developed a novel method to detect the susceptibility of Neisseria gonorrhoeae to the antibiotic cefixime.
Novel Fret Method
Dr. Jiayu Liao and colleagues at the University of California, Riverside have developed a FRET assay using nitrobenzoxadiazole (NBD) and coumarin (CUM) amino acid analogs as a FRET pair. These fluorophores are genetically encoded into peptides and proteins surrounding a protease cleavage site or ligand binding site and used for FRET-based high throughput screening for enzymes or small molecule inhibitors involved in pathways such as SUMOylation. Researchers have demonstrated FRET for peptides encoded with NBD and CUM separated by 4 and 6 amino acids and excited at 340 nm (Figure 1). Figure 1. Fluorescent intensity of peptide I (6 amino acids between CUM and NBD) and II (4 amino acids between CUM and NBD) excited at 340 nm.
Novel Non-Antibody-Based Chimeric Antigen Receptor Against HIV That Also Protects Cells From Infection
UCLA researchers in the Department of Medicine have developed a novel chimeric antigen receptor (CAR) that targets T cells against HIV while protecting T cells from HIV infection.
Novel Protease for Oncology and Inflammatory Diseases
The technology is a novel protease that reduces the ability of cells to respond to the inflammatory cytokine Tumor Necrosis Factor (TNF). High TNF levels have been linked to rheumatoid arthritis, Crohn’s disease and many types of cancers.
Treatment Of Lysosomal Storage Disorders
UCLA researchers in the Departments of Neurology have developed a novel treatment for Lysosomal-storage diseases (LSDs) with neurological impairment.
Novel Sources of Hematopoietic Progenitor Cells
UCLA researchers in the Department of Urology have developed a novel method of collecting hematopoietic stem cells from deceased donors that preserves the donor body and organs for further donations.
Plod3-Targeted Anti-Cancer Treatment
UCLA researchers in the department of Dentistry have developed a novel anti-cancer treatment that directly targets enzyme expression necessary to sustain cancer growth.
A Built-In Mechanism Of Gas Maintenance In Microfeatures On A Submerged Surface
UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel superhydrophobic surface for drag reduction and anti-biofouling applications.
CRF Signaling And Hair Growth
UCLA researchers in the department of Medicine have developed a novel method to treat hair loss and potentially circumvent the common complications that rise from current treatments.
New Molecular Tweezers Against Neurological Disorders And Viral Infections
UCLA researchers in the Department of Neurology with an international team of scientists have developed several new molecular tweezer derivatives with novel synthesis methods that significantly improved the therapeutic efficacy and pharmacokinetic characteristics of the drug candidates.
Antibody-Free Protocol For Generation Of Highly Expandable, Non-Fibroadipogenic Mesodermal Precursors from Human Pluripotent Stem Cells For Treatment
UCLA researchers in the Department of Orthopaedic Surgery have developed a novel method to generate mesodermal precursors from human pluripotent stem cells to treat chronic skeletal muscle atrophy and fibrosis.
Massively Parallel High Throughput Single Cell Electroporation (MSEP)
UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel massively parallel, single cell electroporation platform (MSEP) that is high throughput, efficient, and maintains cell viability.