Microscopy System

Abstract

Researchers at the University of California, Davis have developed a microscopy system combining optical coherence and confocal fluorescence microscopy for accurate Dry Eye Disease diagnosis.

Full Description

This technology introduces an innovative microscopy system that integrates multimodal optical coherence microscopy (OCM) with a confocal fluorescence microscope (CFM) to enhance the diagnosis of Dry Eye Disease (DED). By capturing and combining depth-sectioned cross-sectional images with contrast images of fluorescent molecule-labeled cells, it offers a superior visualization of the eye surface, enabling precise detection and diagnosis of DED and other corneal conditions.

Applications

• Diagnostic imaging centers specializing in eye diseases. 
• Research institutions focusing on ocular conditions and treatments. 
• Development of diagnostic devices and systems for the healthcare industry. 
• Pharmaceutical companies for the testing and validation of new treatments for Dry Eye Disease. 
• Integration into clinical practices for routine eye health assessments.

Features/Benefits

• Enhances image quality by integrating OCM and CFM technologies. 
• Captures both depth-sectioned cross-sectional and contrast images for a comprehensive eye examination. 
• Improves accuracy in diagnosing Dry Eye Disease and other corneal conditions. 
• Detects specific fluorescent molecules, enabling precise disease identification. 
• Supports a variety of fluorescent molecules, offering flexibility in diagnostics. 
• Overcomes challenges in accurately diagnosing Dry Eye Disease, which currently relies on patient symptoms and routine testing. 
• Expands visualization capabilities beyond traditional microscopy systems to identify DED. 
• Provides a precise and comprehensive method for examining the corneal surface.

Patent Status

Patent Pending