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Novel Therapeutic Use of the Thyroid Hormone Receptor Beta (THR-ß) Agonist Resmetirom in Congestive Heart Failure
Researchers at the University of California, Davis have demonstrated that THR-β agonists such as resmetirom, when repurposed, can effectively treat heart failure with preserved ejection fraction (HFpEF), addressing unmet clinical needs.
Plants as Platform for the Biosynthesis of Melanin
Researchers at the University of California, Davis have developed a scalable, plant-based method using somatic embryogenesis to produce high yields of water-soluble melanin externally from walnut tissues.
Scaffolded DNA Synthesis
Together with Researchers at the University of Texas at Austin, researchers at the University of California, Davis have developed a method for synthesizing long polynucleotides using scaffolded cooperative binding and enzymatic ligation to improve yield, modification compatibility, and assembly accuracy.
Filamentous Fungal Biomass as a Novel Biomaterial for Cultured Meat Production
Researchers at the University of California, Davis have developed a scalable and sustainable method using edible fungal pellets as microcarriers to grow animal cells for cultivated meat production.
Non-Invasive AI-Based Retinal Inflammation Detection and Severity Estimation Using OCT B-Scans
Researchers at the University of California, Davis have developed a machine learning system that accurately detects and estimates retinal inflammation severity in uveitis patients using non-invasive OCT B-scan images.
Systems, Methods, and Media for Determining Fetal Photoplethysmography Information from Non-Invasively Obtained Mixed Photoplethysmography Signals
Researchers at the University of California, Davis have developed a system and method for accurately extracting fetal photoplethysmography information from mixed maternal-fetal signals obtained non-invasively through the maternal abdomen.
Additional Glycosyl Hydrolase is Critical to Bacteria’s Ability to Consume HMOs
Researchers at the University of California, Davis have developed technology that enables enhanced growth and colonization of beneficial gut bacteria through bacterial expression of heterologous alpha-fucosidases which target human milk oligosaccharides (HMOs), promoting a healthy gut microbiome.
Prebiotic Oligosaccharides
Researchers at the University of California, Davis have developed alacto-oligosaccharide (GOS) formulations selectively promote growth of beneficial Bifidobacteria species by tailoring oligosaccharide chain lengths.