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Combined Individual Nanomaterial Enhancements for Total X-Ray Enhancement

Researchers at the University of California, Davis have developed a method to combine individual nanomaterial enhancements to achieve greater X-ray enhancement.

Near Infrared Fluorescent Imaging Used to Assess Tissue Perfusion in Surgery

Near infrared (NIR) fluorescence imaging (FI) utilizing the fluorophore indocyanine green (ICG) has become more popular for use in medical diagnostics. It is useful for assessing tissue perfusion in a number of surgeries, particularly abdominal, heart, plastic, hepatic as well as other areas of medicine. The light needed for the excitation of the fluorescence is generated by a near infrared light source which is attached directly to a camera. A digital video camera allows the absorption of the ICG fluorescence to be recorded in real time, which means that perfusion can be assessed and documented. Currently, ICG provides a visual representation of tissue perfusion as a global view. Although some efforts have been put into density analysis, no device or software currently performs dynamic evaluation of blood flow for a surgeon. Without objective dynamic measurements, practitioners are only limited to snap shot view of the static environment. This is a problem because it is the dynamics of blood flow that determines tissue perfusion, not how much blood present at a stationary point in time. Furthermore, because there are no numerical evaluations out on the market that can capture this dynamic aspect of blood flow, practitioners are forced to use the naked eye to make a clinical decision that is not only subjective, but is difficult to assess between cases.

Developing Physics-Based High-Resolution Head And Neck Biomechanical Models

UCLA researchers in the Department of Radiation Oncology at the David Geffen School of Medicine have developed a new computational method to model head and neck movements during medical imaging/treatment procedures.

Biologically Applicable Water-Soluble Heterogeneous Catalysts For Parahydrogen-Induced Polarization

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method of parahydrogen-induced polarization in water using heterogeneous catalysts.

Breast Lesion Characterization Using Contrast Mammography

Breast cancer is the most common cancer in women in the U.S. As with any cancer, early detection and treatment is critical in minimizing the severity of the tumor and risk of death. Researchers at UCI School of Medicine have developed a novel contrast-enhanced mammography technique capable of distinguishing between benign and malignant lesions in breast tissue.

Simultaneous Corneal Hydration Thickness And Hydration Measurement Through Multi-Spectral Reflectometry

UCLA Researchers in the Department of Bioengineering have developed a novel technology to simultaneously detect changes in thickness and hydration levels of the cornea.

Scanning Method For Uniform, Normal-Incidence Imaging Of Spherical Surface With A Single Beam

UCLA researchers have created a method that achieves uniform normal-incident illumination of a spherical surface by first projecting the sphere onto a Cartesian plane and then raster scanning it using an illuminating beam. This allows the scanned object, the illumination source, and the detector to remain stationary.

Assessment Of Wound Status And Tissue Viability Via Analysis Of Spatially Resolved Thz Reflectometry Maps

UCLA researchers in the Department of Bioengineering have developed an algorithm to assess the burn wound severity and predict its future outcomes using Terahertz imaging.

Time-Resolved Fluorescence Imaging Without Lifetime Fitting

UCLA investigators have developed a novel method to obtain time-resolved fluorescence imaging (TRFI) without the need to extract a fluorescence lifetime. Compared to conventional TRFI, this novel method is reliable, simple, time-saving and can dramatically improve biomedical applications of TRFI.

A Method For In Magnetic Resonance Perfusion Weighted Images

UCLA researchers in the Departments of Radiological Sciences and Neurology have developed a novel algorithm for processing perfusion weighted magnetic resonance images.

Estimation Of Contrast Concentration From Angiograms In Presence Of Vessel Overlap

UCLA researchers have developed an image processing technique for quantitative measurement of brain hemodynamics using x-ray digital subtraction angiography (DSA) images. 

Non-Invasive Method For Determination Of Tissue Electrical Conductivity

UCLA researchers in the UCLA Semel Institutes of Neuroscience and Behavior have developed a non-invasive method to locate and estimate electrical currents in organs such as the brain and heart.

Revolutionizing Micro-Array Technologies: A Microscopy Method and System Incorporating Nanofeatures

UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree incoherent holographic microscope using a plasmonic aperture.

Holographic Opto-Fluidic Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a system for holographic opto-fluidic microscopy.

Lensfree Super-Resolution Holographic Microscopy Using Wetting Films On A Chip

UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree super-resolution holographic microscope using wetting films on a chip.

Fluorescent Imaging Of Single Nano-Particles And Viruses On A Smart-Phone

UCLA researchers in the Department of Electrical Engineering have developed a novel field portable fluorescence microscope that can be used as a smart phone accessory.

High-Throughput And Label-Free Single Nanoparticle Sizing Based On Time-Resolved On-Chip Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a rapid, low-cost, and label-free methodology for nanoparticle sizing.

Pixel Super-Resolution Using Wavelength Scanning

UCLA researchers have developed a novel way to significantly improve the resolution of an undersampled or pixelated image.

Microscopic Color Imaging And Calibration

UCLA researchers in the Department of Electrical Engineering have developed a color calibration method for lens-free and mobile-phone microscopy images allowing for high resolution and accurate color reproduction.

Wide-Field Imaging Of Birefringent Crystals In Synovial Fluid Using Lens-Free Polarized Microscopy For Crystal Arthropathy Diagnosis

UCLA researchers in the Department of Electrical Engineering have developed a new diagnostic tool for arthropathic diseases, such as gout.

Single Molecule Imaging and Sizing of DNA on a Cell Phone

UCLA researchers in the Department of Electrical Engineering have developed a light-weight and cost-effective fluorescence microscope installed on a cell phone.

A Method For Measuring Cardiac Timing From A Ballistocardiogram

UCLA researchers have developed an algorithm to directly measure the cardiac timing from Ballistocardiogram (BCG) to help cleaning the BCG from the Electroencephalogram (EEG) recording.

Methods For The Identification And Targeting Of Brain Regions And Structures

A UCLA physician has developed a method to identify regions of the brain using Diffusion Tensor Imaging MRI to locate afferent and efferent neural tracts that lead to and from the specific region of interest. This technique will improve the accuracy and safety of brain treatments, such as electrical brain stimulation and ultrasound imaging.

Label Free Assessment Of Embryo Vitality

Researchers at UC Irvine developed an independent non-invasive method to distinguish between healthy and unhealthy embryos.

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