X-ray-induced Acoustic Computed Tomography (XACT) for In Vivo Dosimetry

Tech ID: 34113 / UC Case 2021-729-0

Brief Description

This technology leverages X-ray-induced acoustic phenomena for real-time, in-line verification of photon beam location and dose during cancer radiotherapy.

Full Description

X-ray-induced Acoustic Computed Tomography (XACT) utilizes the conversion of X-rays to acoustic waves through thermoelastic expansion, enabling the imaging of acoustic waves generated by X-ray absorption in tissues. This process allows for the monitoring of radiation dose and beam alignment during radiotherapy, ensuring precise targeting and dose delivery to cancerous tissues.

Suggested uses

  • Real-time dosimetry in radiotherapy for cancer treatment. 
  • Enhancement of precision in radiation therapy through in-line verification. 
  • Integration into existing radiotherapy equipment to improve treatment outcomes. 
  • Development of new radiotherapy devices with built-in XACT technology.

Advantages

  • Real-time monitoring of radiation dose and beam location. 
  • Non-invasive in vivo dosimetry for enhanced treatment safety. 
  • Ability to detect geometric and morphological misalignments of the X-ray field. 
  • Improves the precision and effectiveness of radiotherapy treatments. 
  • Linear correlation between acoustic signal strength and X-ray dose deposition for accurate dosimetry.

Patent Status

Country Type Number Dated Case
Patent Cooperation Treaty Reference for National Filings WO 2022/081763 04/21/2022 2021-729
 

Patent Pending

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