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Wirelessley Powered Stimulator

UCLA researchers in the Department of Electrical and Computer Engineering have developed a battery-less implantable pulse generator with concise circuitry and mm-scale form factor.

Mechanisms and Devices Enabling Arbitrarily Shaped, Deep-Subwavelength, Acoustic Patterning

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a Compliant Membrane Acoustic Patterning (CAMP) technology capable of patterning cells in an arbitrary pattern at a high resolution over a large area.

Handle Mechanism And Functionality For Repositioning And Retrieval Of Transcatheter Heart Valves

Improved catheter devices for delivery, repositioning and/or percutaneous retrieval of percutaneously implanted heart valves are described, including a medical device handle that provides an array of features helpful in conducting a percutaneous heart valve implantation procedure while variously enabling radial expansion or contraction and/or lateral positioning control over the heart valve during the medical procedure.

Nanoparticles-Enabled Casting of Bulk Ultrafine Grained/Nanocrystalline Metals

UCLA researchers in the Department of Mechanical and Aerospace engineering have fabricated bulk, thermally stable ultrafine grained/nanocrystalline metals using conventional casting techniques.

Liquid Metal Enabled Multi-Functional Neural Probes with Ultra-Large Tunable Stiffness

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel multi-functional neural probe with ultra-large tunable stiffness for electrochemical sensing and chemical delivery in the brain.

Methods For Development Of Hybrid Tissue Engineered Valve With Polyurethane Core

A hybrid tissue engineered heart valve leaflet including a polyurethane core, such as a polycarbonate-based thermoplastic polyurethane like carbothane. The polyurethane core is enclosed within one or more layer of a patient's cells and collagen. Also disclosed are hybrid tissue engineered heart valves, including a frame; and at least two leaflets attached thereto in a configuration of a heart valve, wherein the leaflets are hybrid tissue engineered heart valve leaflets, and methods of making a hybrid tissue engineered heart valve for deployment in a patient.Patent application publication no. US20190151509A1 

Multi-Stage Wireless Powering Mechanism for Long-Term Implantable Medical Devices

UCLA researchers in the Department of Bioengineering have developed a novel invention for wirelessly powering long-term implantable medical devices.

Bioresorbable Orthopedic Implants

Prof. Huinan Liu and her colleagues at the University of California, Riverside have developed a bioresorbable nutrient-based magnesium alloy that may be used for repairing fractured bones. This alloy offers comparable mechanical strength to current metal implants, and safely degrades in vivo to natural metabolic products with a controlled degradation rate. In addition, the degradation products of this alloy induce bone regrowth and promote fracture healing. Fig. 1: Illustration of bioresorbable nutrient-based magnesium alloys for repairing bone fractures.  

3D Printed Normal Force Sensor

UCLA researchers in the Department of Bioengineering have developed a novel 3D printing method that produces customizable normal force sensors for robotic surgical applications at high speed and low cost.

Semi-Implantable Hearing Aid

Inventors at UCI have developed a semi-implantable hearing aid that provides similar sound clarity to an implanted device. The UCI device allows sound to be transmitted to the inner ear without invasive surgery. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:8.0pt; mso-para-margin-left:0in; line-height:107%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} table.MsoTableGrid {mso-style-name:"Table Grid"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-priority:39; mso-style-unhide:no; border:solid windowtext 1.0pt; mso-border-alt:solid windowtext .5pt; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-border-insideh:.5pt solid windowtext; mso-border-insidev:.5pt solid windowtext; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

Calibration Of Continuous Blood Pressure

Brief description not available

Manumeter for Monitoring and Assessing Upper Extremity Rehabilitation

After an injury or neurological event, a patient’s rehabilitation requires long-term assessment and monitoring, especially in the upper extremities that are important for everyday tasks.UCI researchers have developed the Manumeter to quantitatively assess and log a patient’s hand movements without external therapist intervention.

Bioresorbable Electrodes for Recording, Stimulation, and Drug Delivery

Prof. Huinan Liu and her colleagues from the University of California, Riverside have developed new magnesium based bioresorbable electrodes capable of recording, stimulating, and repairing neural tissues for a wide range of diseases and injuries. These new electrodes degrade naturally in aqueous physiological environments and eliminate the need for surgical removal of the implanted electrodes. This technology would benefit both doctors, patients, and researchers by introducing a new generation of neural electrodes that minimize damage to neural tissue while providing the option of drug delivery with the conductive polymer coating.

A Wearable Platform for In-Situ Analysis of Hormones

UCLA researchers in the Department of Electrical and Computer Engineering have developed a highly sensitive, wearable hormone monitoring platform.

Ultra-Low Cost, Transferrable and Thermally Stable Sensor Array Patterned on Conductive Substrate for Biofluid Analysis

UCLA researchers from the Department of Electrical Engineering have invented a novel biosensor array that is ultra-low cost and thermally stable. It prolongs the lifetime of electrode modules of sensor products and allows for extended sensing operation in uncontrolled environments.

Wearable Monitor of Attentional Integrity and Mental Strain

UCLA researchers in the Department of Psychiatry & Biobehavioral Sciences have developed a novel brain monitoring device that can be worn inconspicuously.

Biomimetic Interfaces For Biodegradable Metallic Implants

Prof. Huinan Liu and her colleagues from the University of California, Riverside have developed a novel material that may be used for bioresorbable implants.  The degradation rate of Mg and its alloys in the materials are controlled through the use of a functional nanocomposite coating. Nanophase ceramic/polymer composite coated Mg provides promising properties and nano-scale surface features for the use as the next-generation biodegradable implant materials. This technology would benefit both doctors and patients, as orthopedic devices made of these materials would eliminate the need for implant removal surgery. Fig. 1A An SEM image of a PLGA coated Mg substrate Fig. 1B An SEM image of a nHA/PLGA coated Mg substrate  

Titanium Implants with Novel Roughness

UCLA researchers in the School of Dentistry at the Weintraub Center for Reconstructive Biology have developed a novel titanium implant with hierarchical multi-scale roughness to promote bone growth.

In-Situ Sweat Rate Monitoring For Normalization Of Sweat Analyte Concentrations

UCLA researchers in the Department of Electrical Engineering have developed a method of in-situ sweat rate monitoring, which can be integrated into wearable consumer electronics for physiological analyses.

Novel Adjustable Caliber Catheter System

UCLA researchers in the Department of Radiological Sciences have designed a new adjustable catheter system for use in embolectomy or thrombectomy procedures.

A Novel Device for the Measurement of the Strength of the Orbicularis Oculi Muscle

UCLA researchers in the Department of Ophthalmology have developed a novel device that measures the strength of the orbicularis oculi muscle.

Crosslinkable Polymer Coating Prevents Bacterial Infection on Implant Surface

UCLA researchers in the Department of Orthopedic Surgery have developed a polymer implant coating that mitigates bacterial infections on the implant surface.

Heart Assist Device for Patients

Researchers at UCI have developed a cardiac assist device for patients with failing heart functions. The device contracts and expands the heart with the help of a pacemaker to help restore natural heart pace and blood flow. 

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