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Intraprocedural Grid Localization System

Brief description not available

Non-invasive Head and Neck Cancer Screening Probe based on Optical Coherence Tomography

Researchers at the Beckman Laser Institute have developed a non-invasive fiber optic probe capable of imaging and detecting cancerous tissue within the head and neck regions. The probe also helps to guide surgeons in effectively performing tumor removal.

A Voice Inversion System To Estimate Vocal Fold Properties From Voice Acoustics

Prof. Zhang in the Department of Head and Neck Surgery has developed a voice inversion system that assesses the physiological state underlying voice production. The system can be used to diagnose vocal fold disorders as well as determine the emotional state of a speaker.

Polarization-Sensitive Optical Coherence Tomography Using a Polarization-Insensitive Detector

A polarization-sensitive optical coherence tomography (PS-OCT) is a common approach to non-invasively imaging in biomedical applications. The inventors have come up with a new way of creating a PS-OCT that is cheaper and simpler.

A Piezoelectric Drug Delivery System

Prof. Jin Nam and colleagues from the University of California, Riverside have developed a stimulus-responsive drug delivery system, based on electrospun piezoelectric nanofibrous membranes. The drug release characteristics of these nanofibers can be fine-tuned by modulating their piezoelectric properties via fiber size control, thus the sensitivity of the material to the magnitude and frequency of the applied pressures. In this regard, stimuli-responsive drug delivery systems are promising methods in overcoming the pharmacogenetics associated vulnerabilities in response to systemic drug administration, by controlling when, where, and how much drug is released to accommodate a more personalized therapy.  Fig 1: Model drug release from nanofibrous membranes composed of 70 nm average fiber diameter in vivo in response to mechanical stimulation. The membranes were conjugated with a fluorescence dye (Vivotag) and implanted under vastus lateralis near femur in rats. The release of the drug under non-invasive mechanical activation was determined by in vivo fluorescence imaging. ** indicates p < 0.01.  

The Uro-Wheel

Though guidewires are a common part of many endoscopic procedures as they help the scope reach its desired organ successfully, they are often difficult to maneuver due to their flexible and slippery construction. To combat this and assist physicians in rapid and effective endoscopic placement, researchers at UCI have developed a novel device which, by a simple turn of a finger wheel, allows the guidewires to be automatically and controllably advanced and retracted.

Personalized Oncology Drug Efficacy Monitoring Chip

Researchers at UCI have developed a novel microfluidic-based platform that enables personalized drug screening of patient-derived cancer cells. This versatile device features real-time, continuous screening of patient samples without the need for expensive labeling reagents, large sample sizes, or bulky readout equipment.

The Vaccushield Aka Slacc (Suction-Assisted Local Aerosol Containment Chamber)

UCLA researchers in the Department of Anesthesiology and Perioperative Medicine have developed a device that can act as a protective barrier for healthcare workers from patients with contagious respiratory pathogens.

A Wearable Freestanding Electrochemical Sensing System

Researchers in the UCLA Department of Electrical and Computer Engineering have developed a strategy for high-fidelity, wearable biomarker data acquisition and sensor integration with consumer electronics.

A Thin Film Nitinol Neurovascular Covered Stent For Small Vessel Aneurysms

UCLA researchers in the Department of Pediatrics have developed a thin and flexible stent that can be implanted in small vessels in the neurovascular system. Normal 0 false false false EN-US ZH-CN X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

A Fully Integrated Stretchable Sensor Arrays for Wearable Sign Language Translation To Voice

UCLA researchers in the Department of Bioengineering have developed a novel machine learning assisted wearable sensor system for the direct translation of sign language into voice with high performance.

Insulin Infusion Cannulas with Superior Performance

Researchers at UCI have developed the application of a biocompatible material to insulin infusion devices for Type 1 Diabetes to improve device strength, reduce scar tissue buildup, and increase the efficiency of insulin delivery.

Laser Additive Manufacturing Method For Producing Porous Layers.

A method of metal additive manufacturing which allows for production of porous products with pore size potentially down to the nanometer-scale.

Fluorescence Lifetime Imaging Microscopy Device for Antibiotic Susceptibility Testing (FLIM-AST)

Antibiotic resistant bacterial infection is a global public health threat leading to prolonged hospital stays, higher medical costs, and increased mortality rates. UCI researchers developed a device to rapidly determine antibiotic susceptibility of bacteria from patient samples to determine more effective antibiotic treatments.

A Wireless Textile Based Sensor System for Self-Powered Personalized Health Care

UCLA researchers in the Department of Bioengineering have developed a textile-based sensor system (TS system) for wireless, wearable biomonitoring.

Unobtrusive Fetal Heartrate Monitoring In The Daily Life

A novel wearable, unobtrusive flexible patch designed to facilitate continuous monitoring of fetal heart rate (fHR) and ECG by pregnant women in a home setting.

New And Integrated Method For Continuous Auditory Brain Stimulation

Various examples of delivering continuous auditory stimulation of various kinds (sometimes referred to by the term “entrainment”) have been proposed to modulate brainwaves for therapeutic effect. Current methods of delivering continuous auditory stimulation typically present noises (in the form of clicks, tones, pulses) embedded in music. By modulating the user’s existing audial environment to embed continuous auditory sound stimulation, this technology creates a more tolerable and user-friendly experience that enables prolonged therapeutic stimulation for such neurodegenerative disorders as Alzheimer’s, Parkinson’s and Chronic Traumatic Encephalopathy (CTE).

Wireless and Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans Immersed in Virtual, Augmented or Real-World Environments

UCLA researchers in the Department of Psychiatry and Biobehavioral Sciences have a designed a lightweight, highly mobile deep brain activity measuring platform that elucidates neural mechanisms for neuropsychiatric disorders.

High Resolution Laser Speckle Imaging of Blood Flow

Prof. Guillermo Aguilar and his colleagues from the University of California, Riverside have developed a new approach to laser speckle imaging, called Laser Speckle Optical Flow Imaging (LSOFI) to be used for autonomous blood vessel detection and as a qualitative tool for blood flow visualization. LSOFI works by capturing the speckle displacement caused by different physical behavior and use the data to create a mapped image. It has been shown that LSOFI has many advantages over LSCI methods both in temporal and spatial resolution. Namely, LSOFI can be used to produce higher resolution images compared with the LSCI method using less frames. Combining this technology with Graphics Processing Unit (GPU) computation increases the speed of LSOFI, so GPU enabled LSOFI shows potential to create a fast and fully functional quasi-real time blood flow imaging system.  Fig 1: Comparison of blood flow imaging techniques applied to the raw image. The shown results are for Laser Speckle Optical Flow Imaging (LSOFI) using the Farneback Optical Flow algorithm, traditional Laser Speckle Imaging (LSI), and Temporal Frame Averaging (sLASCA).  

Zinc Nanocomposites And Stents For Functional Applications

UCLA researchers in the Department of Mechanical Engineering have developed a method to manufacture zinc-based metal matrix nanocomposites (MMNCs) for functional applications, such as stents.

Mattress for Bed Sore Prevention

UCLA researchers in the Department of Mechanical and Aerospace Engineering have designed a low-cost, lightweight and easily adjustable mattress that prevents bed sores.

Detection of Tetrahydrocannabinol (THC): Toward a Marijuana Breathalyzer

UCLA researchers in the Department of Chemistry and Biochemistry have developed the fundamental technology for a device that can measure the amount of tetrahydrocannabinol (THC), a common psychotropic substance found in marijuana.

Mediator-Free Electroenzymatic Sensing with Enhanced Sensitivity and Selectivity for Wearable Metabolite and Nutrient Monitoring Applications

UCLA researchers in the Department of Electrical and Computer Engineering have developed a wearable electroenzymatic sensor for non-invasive monitoring of metabolites and nutrients. The sensor has been successfully tested in human subjects to be highly sensitive and selective, making it ideal for monitoring and improving individual well-being.

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