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Novel Methodology To Convert Magnetic Resonance Imaging Scan Data To Be Used In Proton Beam Therapy

This invention is a novel model that uses magnetic resonance imaging (MRI) information to more accurately determine the irradiation area using proton beam therapy (PBT) for oncological treatment.

An Electro-Optical System with a Computation Model for Scanning Human Body

The invention describes an Electro-Optical instrument and a computational model for functional scanning of human body and recovering its chromophores (water, lipid, oxygenated hemoglobin, and deoxygenated hemoglobin). It is a low cost portable system that integrates frequency domain and continuous wave domain for real time spectroscopic imaging of human tissue.

Percutaneous Arteriovenous Fistula For Dialysis Access

This implantable medical device can be used to create an arteriovenous fistula (AVF) percutaneously, in a clinic based procedure. The AVF improves clinical outcomes for  patients  on hemodialysis.

Computational Out-Of-Focus Imaging Increases The Space-Bandwidth Product In Lens-Based Coherent Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a wide-field and high-resolution coherent imaging method that uses a stack of out-of-focus images to provide much better utilization of the space-bandwidth product (SBP) of an objective-lens.

Sparsity-Based Multi-Height Phase Recovery In Holographic Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a sparsity-based phase reconstruction technique implemented in wavelet domain to achieve more than 3-fold reduction in the number of holographic measurements for coherent imaging of densely connected samples with minimal impact on the reconstructed image quality.

Artificial Hair Transplantation

UCLA researchers in the Department of Head and Neck Surgery have developed a novel bio-inert scaffold with artificial hairs to be inserted in the scalp to artificially restore hair.

The Use of Voltammetry Based Assessment of Neurotransmitters and Metabolites in Vivo

UCLA researchers in the Departments of Medicine, Radiology and Bioengineering have developed novel methods for monitoring cardiac autonomic function in vascular and tissue compartments by measuring neurotransmitters and metabolites in vivo.

Oro-Nasogastric Tube Insertion Device

Gastric intubation is a critical part of patient care during surgical procedures, though the insertion of such tubes has up to a 50% failure rate. Researchers at UCI have developed a device that allows for accurate placement of nasal and oral gastric tubes, which in addition to being simple and inexpensive, reduces the risk of accidental tube misplacement and organ perforation.

Single Ended Draw Lines For Medical Device Application

Minimizing the movement of deployed transcatheter heart valves and stents during detachment using single ended draw lines.

A Method to Protect the Esophagus and Other Mediastinal Structures During Cardiac and Thoracic Interventions

UCLA researchers in the Division of Cardiology at the Geffen School of Medicine have developed a novel device that provides protection of esophagus and other surrounding mediastinal structures when the pericardial space is accessed by interventional catheters/probes.

A Novel Method and Apparatus to Access the Left Heart for Cardiac Interventions

UCLA researchers in the Division of Cardiology at the Geffen School of Medicine have developed novel devices and methods for allowing entirely intravascular access to the left ventricle, thereby precluding access via the apex of the heart percutaneously or by surgery.

Portable Breath Sampler for Diagnostic Testing

Researchers at the University of California, Davis have developed a portable, human exhaled breath sample collector for use in breath tests.

Deep Brain Stimulation for the Treatment of Post-Traumatic Stress Disorder, Anxiety Disorders, and Disorders with Psychotic Features

UCLA researchers have developed a novel therapeutic strategy to alleviate post-traumatic stress disorder (PTSD) symptoms via deep brain stimulation.

Non-Invasive Bladder Volume Sensing Device

Researchers at the University of California, Davis have developed an apparatus and methods for non-invasive bladder volume sensing, to determine when a patient’s bladder is full.

Endoscopic, Laparoscopic, Robotic And Minimally Invasive Force Sensor And Monitoring System

Minimally invasive ureteroscopy is a common procedure in adults, with over 10,000 procedures conducted annually in California alone. The ureteral access sheath (“UAS”), a highly effective device used to facilitate minimally invasive ureteroscopy, can injure the patient when excessive force is used during its placement. Inventors at UCI have developed a minimally invasive force sensor and monitoring system that measures force during UAS placement and can preclude injury by alerting the physician when the threshold for injury is being approached. It thus can be used for medical personnel safety training, quality control and standardization of minimally invasive ureteroscopy, as well as being applied to the passage of other catheters into natural orifices or channels./

Handled Blood-Flow Imaging Device

The invention is a medical handheld device that carries out skin visual inspection simultaneously with blood flow measurements through integrating a Laser Speckle Imaging (LSI) system within a handheld compact dermoscope. Combining both features in one compact, cheap and easy to use device will generate accurate and elaborative functional data that will improve the accuracy and detection of diseases such as cancer.

Wireless In Situ Sensors in Stents for the Treatment and Monitoring of Chronic Obstructive Lung Disease (COPD)

UCLA researchers in the Department of Electrical Engineering have developed a novel wireless sensor for external and internal biosensing applications.

Exercise Promotion, Measurement, and Monitoring System

UCLA researchers in the Department of Electrical Engineering have developed a novel wireless sensor and exercise system for real-time exercise promotion and monitoring.

Novel Anti-Bacterial, Anti-Fungal Nanopillared Surface

Medical devices are susceptible to contamination by harmful microbes, such as bacteria and fungi, which form biofilms on device surfaces. These biofilms are often resistant to antibiotics and other current treatments, resulting in over 2 million people per year suffering from diseases related to these contaminating microbes. Death rates for many of these diseases are high, often exceeding 50%. Researchers at UCI have developed a novel anti-bacterial and anti-fungal biocomposite that incorporates a nanopillared surface structure that can be applied as a coating to medical devices.

Handheld Device to Detect Ear Infections

Acute otitis media (AOM) is a painful ear infection with a high incidence rate in children. Despite its prevalence, it is commonly misdiagnosed especially in the youngest children, in part due to obstruction of the ear canal by earwax. Researchers at UCI have developed a compact, low-cost, adaptable device to diagnose otitis media through LED light absorption. The device is able to diagnose otitis media through earwax that could be obstructing the view of the eardrum.

Nonlinear Optical Photodynamic Therapy of the Cornea for Corneal Disorders, Cancer, and Infection

Inventors at UC Irvine have developed an apparatus and method using nonlinear optical photodynamic therapy (NLO-PDT) for modifying corneal shape and treating progressive corneal astigmatism and refractive errors. The selectively focused femtosecond-near infrared laser light and apparatus improves upon existing methods by providing rapid (< 1min) corneal treatment that minimizes unwanted cellular damage to the eye through precise lateral and axial treatment to the cornea.

Device and Method to Assess Ocular Surface Health

Researchers at the University of California, Davis have developed a diagnostic device and method to determine ocular surface health.

IVC Filter Web Retrieval Device

UCLA researchers have developed a new IVC filter retrieval system that can be used for extraction of the web component of IVC filters.

Novel Surgical Device for Scleral Buckling Retinal Detachment Repair

UCLA researchers in the Departments of Ophthalmology and Engineering have developed a new surgical device used in retinal detachment surgery.

Automated Optical Chest Tube Air Leak Detection System

UCLA researchers in the Department of Surgery have developed an air leak detection system for use in patients requiring chest tube placement.

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These technologies are part of the UC QuickStart program.