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CAPTaINs: Capped And Protected Targeted Immunoproteasome N-End Degrons

CAPTaINs provide a novel, selective, and stable method for selective degradation of protein targets.

The Isolated Heparin-binding Domain (HBD) of VEGF165 and the Isolated D1 Domain of VEGFR2 (KDR)

Researchers at the University of California, Davis have developed recombinant fusion protein compositions that inhibit pathological angiogenesis by targeting VEGF165-KDR interactions to treat cancers and related diseases.

Methods of Improving Cancer Immunotherapy

Researchers at the University of California, Davis have developed methods that combine immunotherapeutic agents with dual inhibitors to enhance cancer treatment efficacy and prolong patient survival.

Programmable Peptide Nucleic Acid-Based Nanoplatform for Customizable Drug Delivery

Researchers at the University of California, Davis have developed a peptide nucleic acid-based system enabling precise and customizable delivery of antigens, adjuvants, and targeting molecules for improved cancer immunotherapy.

Genomic Destructive CRISPR Guide RNAs

Brief description not available

Cherenkov-Based Radiation Beam Monitor

Researchers at the University of California, Davis have developed an innovative Cherenkov-based system for calibrating radiotherapy beams, enabling precise, real-time calibration of radiation dose delivery, including for high-intensity FLASH radiotherapy, improving treatment accuracy and reliability.

A Two-step Drug Delivery System Based on Click Chemistry

Researchers at the University of California, Davis have developed a technology that introduces a TCTS (Two-component Two-step) drug delivery system designed to enhance cancer treatment efficacy while minimizing toxicity.

Macrophage Targeting Peptides - Peptide Sequences that are Specific to M1 And M2 Macrophages for Application in Molecular Imaging and Therapy

Researchers at the University of California, Davis have developed isolated peptides that selectively bind M1 and M2 macrophages to enable precise diagnosis and targeted treatment of macrophage-associated diseases, including cancer.

Nanoplatform for Cancer Therapy

Researchers at the University of California, Davis have developed a nanoparticle system combining photothermal therapy and chemotherapy for enhanced cancer treatment.

Targeting Cancer Cachexia with Soluble Epoxide Hydrolase Inhibitors

Researchers at the University of California, Davis have developed a therapeutic approach to prevent and treat cancer cachexia by inhibiting soluble epoxide hydrolase, promoting resolution of systemic inflammation, mitigating muscle wasting, and improving survival outcomes in preclinical models without inducing toxicity or immunosuppression.

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