Fluorescent Bis-Trifluoromethyl Carborhodamine Compounds

Patent Status

Patent Pending

Brief Description

UCB researchers have developed a novel class of bright, fluorescent rhodamine dyes with a novel structural modification resulting in a deep red shift relative to the parent carborhodamine dye, with the new dye absorbing and emitting near-infrared light in the same region as the commercially successful silicon rhodamine dyes. Biological imaging with near-infrared light is advantageous for numerous biological and surgical applications. 

Furthermore, bis-trifluoromethyl carborhodamines offer improved properties desirable for biological imaging applications due to their unique physical and electronic properties.

Suggested uses

• Biological imaging with near-infrared light