REVEALR Technology for Viral Detection

Brief Description

A novel diagnostic technology offering rapid, accurate, and inexpensive detection, genotyping, and quantification of viral RNA in patient-derived samples, enhancing public health capabilities.

Full Description

REVEALR technology is a cutting-edge diagnostic tool that employs isothermal amplification strategies, specifically designed to address the limitations of traditional qRT-PCR methods in viral detection. Utilizing a unique sequence-specific detection modality, this technology can accurately identify, genotype, and quantify viral RNA signatures in patient-derived samples. This approach allows for the conversion of viral genomes into detectable signals, observable via fluorescence or lateral flow devices, facilitating rapid and precise point-of-care diagnostics.

Suggested uses

• Routine disease diagnosis in clinical settings. 
• Point-of-care testing in remote or resource-limited locations. 
• Public health surveillance and epidemic response. 
• Genotyping for personalized medicine applications, including cancer and infectious disease management.

Advantages

• Rapid detection of viral RNA in less than one hour. 
• High sensitivity with attomolar detection capabilities. 
• High specificity, reducing the risk of false positives through sequence-specific detection. 
• Field deployable, offering significant advantages for public health surveillance.
• Versatile, with the potential for detecting a wide range of viral and bacterial pathogens, as well as genotyping human diseases.

Patent Status

Patent Pending

Related Materials

• Schuder DN, Lu ND, Chaput JC. Revealr-Based Diagnostic Panel for Rapid Detection of Acute Respiratory Infections. ACS Synth Biol. 2024 Dec 20;13(12):4202-4208. doi: 10.1021/acssynbio.4c00644. Epub 2024 Dec 4. PMID: 39630957.