The enhanced electrochemical activity of nanostructured materials is readily exploited in energy devices, but their utility in scalable and human-compatible implantable neural interfaces can significantly advance the performance of clinical and research electrodes. Traditional biologically inert noble metals such as Pt, Ir or IrPt – are preferential material choices for manufacturing nerve electrodes/ biomedical devices in clinical-relevant applications because of their biocompatibility and stability against corrosion, and because of their superior electrochemical properties compared to other material combinations. But despite these superior properties, the electrochemical interface impedance is not sufficiently low to enable recording minute potential fluctuations with low noise baseline or to efficiently inject charges across the interface without building large voltages across the interface and therefore consuming larger powers per pulse. As a result, large electrodes are needed to compensate for this large impedance, but large electrodes compromise spatial resolution and specificity for recording and/or stimulation and limit the density and overall number of contacts. To increase the surface area and decrease the electrochemical impedance, nano-structures are often incorporated onto electrode surfaces to enhance their electrochemical properties. Prior work has successfully incorporated nano-structured Pt into electrodes, using electrochemical methods (electro-plating) , but these electrodes suffered from poor structural integrity and physical strength due to incorporation of electrochemical surfactants at the interface between nano-structured Pt and the underlying electrode. Furthermore, common approaches for the fabrication of nano-structured Pt are generally not monolithic and face additional challenges for translation to clinical practice whereas some are also problematic due to the residual of toxic ligand additives remaining after Pt alloy electro-deposition.