EyeCV: A Novel Tool for Rapid, Accurate, and Reproducible Screening of Endothelial Cell Morphology in Diseased and Healthy Corneas

Tech ID: 34844 / UC Case 2023-517-0

Abstract

Researchers at the University of California, Davis have developed a machine learning-based platform for early, accurate, and efficient detection of endothelial disease from corneal images assessment.

Full Description

This technology is a machine learning solution that efficiently evaluates the morphological features of endothelial cells. The technology includes a custom dataset for training the model, segmentation based on deep learning, and a comprehensive analysis report to assist veterinarians. It serves as a diagnostic tool, removing subjectivity from endothelial cell evaluations and supporting the assessment of treatment outcomes.

Applications

  • Diagnostic tool for detecting endothelial cell diseases in animals. 
  • Platform for tracking disease progression and treatment effectiveness. 
  • Clinical decision support tool for veterinary care. 
  • Potential application in human subjects with appropriate data.

Features/Benefits

  • Fast and accurate evaluation of endothelial cells. 
  • Exceptional dataset for training the model. 
  • Productive platform to assess the efficiency of treatment protocols. 
  • Offers better clinical decision support in veterinary care. 
  • Mitigates time-consuming manual methods for assessing corneal endothelial cells. 
  • Addresses subjectivity and variability in endothelial cell evaluations. 
  • Solves difficulty in tracking disease progression and measuring the impact of treatments.

Patent Status

Country Type Number Dated Case
Patent Cooperation Treaty Reference for National Filings WO 2024/182683 09/06/2024 2023-517
 

Patent Pending

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Inventors

  • Roszak, Karolina
  • Tagkopoulos, llias
  • Thomasy, Sara
  • Youn, Jason

Other Information

Keywords

artificial intelligence, corneal endothelial cell disease, deep learning, disease progression, quantitative morphology

Categorized As

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