A Compact Platform For The Deterministic Assembly Of Microfluidic Droplets

Tech ID: 34517 / UC Case 2019-120-0

Value Proposition

Studying the interactions between biomolecules, reagents, cells or combinations thereof involves bringing such components together under certain conditions. Developments in discrete entity microfluidics have provided tools for manipulating single cells and small volumes of reagents or biomolecules. However, such microfluidic manipulations generally only involve sorting each discrete entity into a particular microfluidic channel. Thus, such microfluidic devices lack the ability to selectively combine discrete entities.

Technology Description

UCSF investigators have developed and demonstrated methods for selectively combining multiple discrete entities (cells, reagents, beads etc) into a single microfluidic droplet for detection and analysis.

Patent Status

Country Type Number Dated Case
Australia Issued Patent 2020275792 10/02/2025 2019-120
United States Of America Issued Patent 12,383,900 08/12/2025 2019-120
China Issued Patent ZL202080050695.8 04/05/2024 2019-120
European Patent Office Published Application 3969176 03/23/2022 2019-120
Canada Published Application 2019-120
Japan Published Application 2019-120
 

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Keywords

cardiovascular, immunology, oncology, high throughput, drug discovery assay, functional assay, microfluidics, droplets

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