Studying the interactions between biomolecules, reagents, cells or combinations thereof involves bringing such components together under certain conditions. Developments in discrete entity microfluidics have provided tools for manipulating single cells and small volumes of reagents or biomolecules. However, such microfluidic manipulations generally only involve sorting each discrete entity into a particular microfluidic channel. Thus, such microfluidic devices lack the ability to selectively combine discrete entities.
UCSF investigators have developed and demonstrated methods for selectively combining multiple discrete entities (cells, reagents, beads etc) into a single microfluidic droplet for detection and analysis.
| Country | Type | Number | Dated | Case |
| Australia | Issued Patent | 2020275792 | 10/02/2025 | 2019-120 |
| United States Of America | Issued Patent | 12,383,900 | 08/12/2025 | 2019-120 |
| China | Issued Patent | ZL202080050695.8 | 04/05/2024 | 2019-120 |
| European Patent Office | Published Application | 3969176 | 03/23/2022 | 2019-120 |
| Canada | Published Application | 2019-120 | ||
| Japan | Published Application | 2019-120 | ||
cardiovascular, immunology, oncology, high throughput, drug discovery assay, functional assay, microfluidics, droplets