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Non-invasive Sleep Quality Measuring Device
Researchers at the University of California, Davis have developed a sleep quality measuring device to measure waking electroencephalogram (EEG) test to determine the adequacy of sleep
O-Acetyl Glycosphingosines and Gangliosides, as well as Their N-Acetyl Analogs
Researchers at the University of California, Davis have developed a technology providing the creation of stable analogs of glycosphingosines and gangliosides containing O-acetylated sialic acid for extensive biological and medical applications.
Electricity enhanced delivery of drugs into the ureter, renal pelvis, and renal parenchyma
The invention entails a unique catheter device utilizing electromotive drug administration (EMDA) to enhance drug penetrance into tissues of the ureter, renal pelvis, and calyces. By incorporating a conductive wire and fluid delivery system, the catheter enables targeted drug delivery, potentially revolutionizing the treatment of kidney stones, urothelial carcinoma, infections, and inflammation without systemic side effects.
Droplet microvortices for modulating cell dynamics
The invention presents a microfluidic platform equipped with specialized trapping arrays and droplet generation capabilities, enabling precise control over the formation of microvortices within cell-laden droplets. This novel system facilitates the study of cell-cell interactions at a single-cell level, offering configurable microenvironments for analyzing cell dynamics and pair relationships.
Fully Automated Multi-Organ Segmentation From Medical Imaging
A comprehensive method for automated multi-organ segmentation based on deep fully convolutional networks and adversarial training, achieving superior results compared to existing techniques.
Direct Drive Hearing Aid Stimulation Methods
An innovative direct drive hearing device, with a removable outside component that allows high quality sound and prolonged usage.
New Cross-Linking Mass Spectrometry Platform: SDASO-L, SDASO-M, and SDASO-S
An innovative mass spectrometry platform that utilizes sulfoxide-containing MS-cleavable heterobifunctional photoactivated cross-linkers to enhance protein structural elucidation.
Compositions And Methods For Wound Healing
A breakthrough technology using insulin-secreting cells and stem cells to enhance wound healing and reduce scar formation.
Affordable and Convenient Neurosurgical Simulator
A cost-effective neurosurgical simulator designed to give neurosurgical residents and medical students a platform to practice and enhance their operative skills.
Imaging of cellular immune response in human skin
This patent application describes methods for non-invasive, label-free imaging of the cellular immune response in human skin using a nonlinear optical imaging system.
High throughput and precision cell sorting
A novel method and device for high-throughput sorting of cells in suspension, particularly focusing on the separation of key cellular blood components of the immune system. The patent application presents a novel approach to high-throughput cell sorting, particularly suitable for applications in medicine and biotechnology where precise separation of cell populations is crucial.
Quantifying optical properties of skin
The disclosed methods offer a robust approach to accurately quantify skin optical properties across different skin tones, facilitating improved diagnosis, monitoring, and treatment in dermatology.
Purification of Glycosphingosines and Glycosphingolipids
Researchers at the University of California, Davis (UC Davis) have developed a simplified procedure to synthesize complex glycosphingosine compounds for the chemical preparation of glycosphingolipids.
System And Method For Tomographic Fluorescence Imaging For Material Monitoring
Volumetric additive manufacturing and vat-polymerization 3D printing methods rapidly solidify freeform objects via photopolymerization, but problematically raises the local temperature in addition to degree-of-conversion (DOC). The generated heat can critically affect the printing process as it can auto-accelerate the polymerization reaction, trigger convection flows, and cause optical aberrations. Therefore, temperature measurement alongside conversion state monitoring is crucial for devising mitigation strategies and implementing process control. Traditional infrared imaging suffers from multiple drawbacks such as limited transmission of measurement signal, material-dependent absorptions, and high background signals emitted by other objects. Consequently, a viable temperature and DOC monitoring method for volumetric 3D printing doesn’t exist.To address this opportunity, UC Berkeley researchers have developed a tomographic imaging technique that detects the spatiotemporal evolution of temperature and DOC during volumetric printing. The invention lays foundations for the development of volumetric measurement systems that uniquely resolve both temperature and DOC in volumetric printing.This novel Berkeley measurement system is envisaged as an integral tool for existing manufacturing technologies, such as computed axial lithography (CAL, Tech ID #28754), and as a new research tool for commercial biomanufacturing, general fluid dynamics, and more.
LaserPack: A burstable liquid storage package for biological material storage and valve substitution
The LaserPack is an easily manufacturable solution for liquid storage in point-of-care devices that is low-cost, has dimensional variability, and is reproducible, while also serving as a valve for liquid access in microfluidic devices. Current liquid storage techniques rely on lyophilization, or freeze-drying, to minimize occupied space, but lyophilization is not applicable to all liquid reagents nor is it optimal for some biological components of point-of-care devices.
A Discrete Color Approach for Stress Mitigation in Medical and Related Healthcare Applications as Applied to the Lighting Of Interiors and/or Medical Apparatus
The California Lighting Technology Center at UC Davis in collaboration with the Center for Mind and Brain have developed a novel lighting technology approach for stress recovery and stress mitigation.
(2023-117) Resilience and Wisdom Training (RWT)
Stress and loneliness are biologically toxic factors with adverse effects on mental and physical health. The 2018 Gallup World Poll found a 25%–40% increase in stress, worry, and anger in the US from 2008 to 2018. Loneliness is associated with considerable distress, and older adults are vulnerable to loneliness due to losses, physical decline, and social isolation. The COVID-19 pandemic led to increased social isolation, though some older adults with higher levels of resilience and wisdom faced the pandemic with greater fortitude than younger adults.Aging is associated with numerous stressors that negatively impact older adults’ well-being. Resilience improves ability to cope with stressors and can be enhanced in older adults. Senior housing communities are promising settings to deliver positive psychiatry interventions due to rising resident populations and potential impact of delivering interventions directly in the community.
Use Of Terpenoids And Salicylates As Anesthetics, Analgesics, And Euthanasia Agents
Researchers at the University of California, Davis have developed agents made from terpenoids and salicylates that can be used as anesthetics in human and non-human animals, as well as environmentally friendly euthanasia agents in food-producing animals.
Polysaccharide A-Based Particulate Systems For Attenuation Of Autoimmunity, Allergy and Transplant Rejection
Researchers at the University of California, Davis have developed a customizable polysaccharide that can be added to nanoparticles to reduce their rejection by the human immune system.
Optimized Non-Addictive Biologics Targeting Sodium Channels Involved In Pain Signaling
Researchers at the University of California, Davis have developed high potency and selective peptide inhibitors that act as a non-addictive analgesic for relief of chronic and/or severe pain in humans.
Cannabigerol (CBG) In The Treatment Of Seizures And Epilepsy
Researchers at the University of California, Davis have developed a method of treating or mitigating seizure, treating epilepsy, as well as a method of reducing the frequency of seizures, using cannabigerol or dihydrocannabigerol and analogs thereof.
Psychoplastogens For Treating Hearing-Related Disorders
Researchers at the University of California, Davis, have developed a novel approach to treat hearing-related disorders with a new type of psychoplastogen that can increase the synapse density in the ear, correlating with hearing ability.
Biocatalytic Asymmetric Synthesis Of Heterocyclic Alpha, Alpha-Disubstituted Amino Acids
Brief description not available
Safety Scalpel for Removal of Gastrostomy Tubes
A researcher at the University of California, Davis has developed a safety scalpel for mitigating the challenges associated with the removal of certain types of percutaneous implants, such as gastrostomy tubes having difficult to reduce anchoring elements.
Vascular Anastomosis Device
Researchers at the University of California, Davis have developed a surgical device to facilitate vascular anastomosis procedures with enhanced ease and speed.