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Membrane Insertion of Potential Sensing Nanorods

UCLA researchers in the Department of Chemistry have developed inorganic semiconductor nanosensors that measure membrane voltage.

Bioorthogonal Ligation Mediated Rare-Cell Capture in Microfluidic Devices

Researchers at the UCLA Department of Molecular and Medical Pharmacology have developed a novel NanoVelcro microfluidic chip that is capable of not only effectively enriching circulating tumor cells (CTCs) but also quickly recovering CTCs with well-preserved mRNA and minimal level of white blood cell contamination.

Label-Free Nanoprobes For Long-Term Imaging Of Organelle Movements In Living Cells

To date, the most widely used technique used to monitor organelle movement in living cells is fluorescent imaging, which requires labelling of organelles. Prior organelle labelling causes disturbance in living cells, which may limit understanding of intracellular organelle movement. Furthermore, conventional fluorescence-based single molecule methods are prone to photobleaching, blinking, and low signal-to-noise ratios.

Microfluidic Interfacial Magnetic Separation (MIMS)

UCLA researchers in the Department of Medicine and Bioengineering have developed a novel magnetic method for sorting cells.

Graphene Nanomesh As A Glucose Sensor

UCLA researchers in the Departments of Chemistry & Biochemistry and of Materials Science & Engineering have developed a glucose sensor based on a graphene nanomesh (GNM) material. The nanoscale GNM glucose sensor provides the potential for in vivo glucose sensing with high selectivity and high sensitivity.

Quantitative Deformability Cytometry: Rapid, Calibrated Measurements Of Cell Mechanical Properties

UCLA researchers in the Department of Integrative Biology and Physiology have developed a novel microfluidic device that enables rapid measurement of cell mechanical properties.

In-Situ TEM Holder With STM Probe And Optical Fiber

Researchers at UCI have developed a fully integrated sample mount for the simultaneous high-resolution imaging and electronic and optical characterization of thin film devices.

High Stability PtNiX-M Electrochemical Catalyst

UCLA researchers in the Department of Material Science and Engineering have invented a novel and highly stable platinum-based catalyst material for fuel cell technologies.

High-Efficiency Ion Source

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a miniature direct-current (DC) ion source with the higher power efficiencies and lower erosion rates needed for space propulsion applications.

High-Throughput Microfluidic Gene-Editing via Cell Deformability within Microchannels

UCLA researchers in the Departments of Pediatrics and Chemistry & Biochemistry have developed a microfluidic device for delivery of biomolecules into living cells using mechanical deformation, without the fouling issues in current systems.

Plasmonic Nanoparticle Embedded PDMS Micropillar Array and Fabrication Approaches for Large Area Cell Force Sensing

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel cell force sensor platform with high accuracy over large areas.

Anti-Ferromagnetic Magneto-Electric Spin-Orbit Read Logic

UCLA researchers in the department of Electrical Engineering have developed a novel magetoelectric device for use as a spin transistor.

Mobile Phone Based Fluorescence Multi-Well Plate Reader

UCLA researchers have developed a novel mobile phone-based fluorescence multi-well plate reader.

Accelerating palladium nanowire hydrogen sensors using engineered nanofiltration layers

Researchers at UCI have developed a method for enhancing existing hydrogen gas sensors, leading to as much as a 20-fold improvement in sensor response and recovery times.

Computational Sensing Using Low-Cost and Mobile Plasmonic Readers Designed by Machine Learning

UCLA researchers have developed a novel method for computational sensing using low-cost and mobile plasmonic readers designed by machine learning.

Process For Electrodepositing Manganeese Oxide With Improved Rate Capabilities For Electrical Energy Storage

The invention is a novel method for enhancing the energy, power and performance of lithium ion batteries. It applies a new process for electrodepositing Manganese Oxide in a way that improves the electrical properties as well as the rate at which the battery can operate. Using this method, the energy storage capabilities is boosted significantly; making it faster, more reliable and enabling various applications to become more dependent on electric/battery solutions.

System and Method for High Density Assembly and Packaging of Micro-Reactors

High density micro-reactors are fabricated to form an array of wells into a surface for use in high throughput microfluidic applications in biology and chemistry. Researchers at the University of California, Irvine developed a method for increasing micro-reactor densities per unit area using rapidly self-assembled three-dimensional crystalline formation droplet arrays, and a device for performing the same.

Scalable Super-Resolution Synthesis Of Core-Vest Composites Assisted By Surface Plasmons

Concurrent control of size, shape, and composition of nanoparticles is key to tuning their functionality with widespread applications in sensing, catalysis, cancer cell ablation, water-splitting, spectroscopy, dye-sensitized solar cells, and more. UCB inventors demonstrate unprecedented precision over the structure and composition of complex nanoparticles by fusing colloidal chemistry with plasmon assisted synthesis.  They show that combining properties of light used for plasmon excitation (wavelength, intensity, and pulse-duration) with the physical properties of nanoparticles (size, shape, and composition) leads to hitherto unrealized core-vest composite nanostructures. Tunable variations in localized temperature distributions >50 degrees C are achieved over nanoparticles as small as 50-100 nm. These temperature variations result in core-vest formations with selective shell coverage that mirrors the local inhomogeneities of the heat distribution. This new class of core-vest nanoparticles (CVNs) allows plasmonic enhancement of nanocomposite functionalities that are inaccessible in typical core-shell geometries.  

Combined Individual Nanomaterial Enhancements for Total X-Ray Enhancement

Researchers at the University of California, Davis have developed a method to combine individual nanomaterial enhancements to achieve greater X-ray enhancement.

A Cavity-Free Self-Referencing Frequency Comb

A self-referencing frequency comb based on high-order sideband generation (HSG) that does not require cavities. Applications include "set-and-forget" optical atomic clocks and high-resolution spectrometers for airborne chemicals.

Revolutionizing Micro-Array Technologies: A Microscopy Method and System Incorporating Nanofeatures

UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree incoherent holographic microscope using a plasmonic aperture.

Rapid, Portable And Cost-Effective Yeast Cell Viability And Concentration Analysis Using Lensfree On-Chip Microscopy And Machine Learning

UCLA researchers in the Department of Electrical Engineering have developed a new portable device to rapidly measure yeast cell viability and concentration using a lab-on-chip design.

Mechanical Process For Creating Particles Using Two Plates

UCLA researchers in the Department of Chemistry and Biochemistry & Physics and Astronomy have developed a novel method to lithograph two polished solid surfaces by using a simple mechanical alignment jig with piezoelectric control and a method of pressing them together and solidifying a material.

Low Cost Wireless Spirometer Using Acoustic Modulation

The present invention relates to portable Spirometry system that uses sound to transmit pulmonary airflow information to a receiver.

Microfluidic Component Package

The present invention describes a component package that enables a microfluidic device to be fixed to a Printed Circuit Board (PCB) or other substrate, and embedded within a larger microfluidic system.

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