Researchers in UCLA's Department of Chemistry and Biochemistry have harnessed gel electrophoresis in order to direct and program controlled collisional reactions between pulse-like bands of molecules and/or colloidal reagent species.

UCLA researchers have developed a novel algorithm that can be used to design unique self-assembled molecules and nanostructures.

Nanoscale multipoint structure-function analysis is essential for deciphering the complexity of multiscale physical and biological systems. Atomic force microscopy (AFM) allows nanoscale structure-function imaging in various operating environments and can be integrated seamlessly with disparate probe-based sensing and manipulation technologies. However, conventional AFMs only permit sequential single-point analysis. Widespread adoption of array AFMs for simultaneous multi-point study is still challenging due to the intrinsic limitations of existing technological approaches.

Microfluidic devices have long been touted as a powerful analytical tool with which to characterize a wide range of analytes, including particles, and cells. Despite the apparent convenience of microfluidic technologies for applications in healthcare, such devices often rely on capital-intensive optics and other peripheral equipment that limit throughput, perhaps because the majority of microfluidic devices operate using optics-based principles, which typically require high-speed or sensitive cameras, sophisticated confocal microscopes, vibration isolation tables, and laser excitation systems.

Researchers at the UCLA Semel Institute for Neuroscience and Human Behavior have developed magnetic nanoparticles (MNPs) functionalized with deoxyglucose that can be used as tissue-specific contrast agents for MRI. These novel MNPs can help physicians and researchers to differentiate neoplastic, epileptic, parkinsonian, or Alzheimer tissues from normal tissue based on the metabolic activity of the tissue.

UCLA researchers in the Department of Civil and Environmental Engineering have invented a novel nanofiltration (NF) and reverse osmosis (RO) composite membrane for water desalination applications.

UCLA researchers in the Department of Electrical Engineering have developed a high-responsivity photodetector that utilizes metallo-graphene nanocomposites for superior detection of infrared wavelengths.

UCLA researchers in the Department of Materials Science and Engineering have developed a novel piezoelectric thin film that can control magnetic properties of individual magnetic islands.

Researchers at UCI have developed a fully integrated sample mount for the simultaneous high-resolution imaging and electronic and optical characterization of thin film devices.

UCLA researchers in the Department of Material Science and Engineering have invented a novel and highly stable platinum-based catalyst material for fuel cell technologies.

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a miniature direct-current (DC) ion source with the higher power efficiencies and lower erosion rates needed for space propulsion applications.

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel cell force sensor platform with high accuracy over large areas.

UCLA researchers in the department of Electrical Engineering have developed a novel magetoelectric device for use as a spin transistor.

UCLA researchers have developed a novel mobile phone-based fluorescence multi-well plate reader.

Researchers at UCI have developed a method for enhancing existing hydrogen gas sensors, leading to as much as a 20-fold improvement in sensor response and recovery times.

The invention is a novel method for enhancing the energy, power and performance of lithium ion batteries. It applies a new process for electrodepositing Manganese Oxide in a way that improves the electrical properties as well as the rate at which the battery can operate. Using this method, the energy storage capabilities is boosted significantly; making it faster, more reliable and enabling various applications to become more dependent on electric/battery solutions.

Concurrent control of size, shape, and composition of nanoparticles is key to tuning their functionality with widespread applications in sensing, catalysis, cancer cell ablation, water-splitting, spectroscopy, dye-sensitized solar cells, and more. UCB inventors demonstrate unprecedented precision over the structure and composition of complex nanoparticles by fusing colloidal chemistry with plasmon assisted synthesis.  They show that combining properties of light used for plasmon excitation (wavelength, intensity, and pulse-duration) with the physical properties of nanoparticles (size, shape, and composition) leads to hitherto unrealized core-vest composite nanostructures. Tunable variations in localized temperature distributions >50 degrees C are achieved over nanoparticles as small as 50-100 nm. These temperature variations result in core-vest formations with selective shell coverage that mirrors the local inhomogeneities of the heat distribution. This new class of core-vest nanoparticles (CVNs) allows plasmonic enhancement of nanocomposite functionalities that are inaccessible in typical core-shell geometries.  

Researchers at the University of California, Davis have developed a method to combine individual nanomaterial enhancements to achieve greater X-ray enhancement.

A self-referencing frequency comb based on high-order sideband generation (HSG) that does not require cavities. Applications include "set-and-forget" optical atomic clocks and high-resolution spectrometers for airborne chemicals.

UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree incoherent holographic microscope using a plasmonic aperture.

UCLA researchers in the Department of Electrical Engineering have developed a new portable device to rapidly measure yeast cell viability and concentration using a lab-on-chip design.

UCLA researchers in the Department of Chemistry and Biochemistry & Physics and Astronomy have developed a novel method to lithograph two polished solid surfaces by using a simple mechanical alignment jig with piezoelectric control and a method of pressing them together and solidifying a material.

The present invention relates to portable Spirometry system that uses sound to transmit pulmonary airflow information to a receiver.

The present invention describes a component package that enables a microfluidic device to be fixed to a Printed Circuit Board (PCB) or other substrate, and embedded within a larger microfluidic system.

Researchers at UC Irvine developed a device and method that combines the high dynamic range and high accuracy of digital PCR (dPCR) with the real-time analysis of quantitative PCR (qPCR) to achieve a ultra-high dynamic range PCR over 10 to 12 orders of magnitude. The present method is accomplished by a highly integrated design that optimally packs, thermocycles, and images as many as 1 million reaction vessels.