Automated Semen Analysis Using Holographic Imaging

Tech ID: 24674 / UC Case 2011-044-0


UCLA researchers in the department of electrical engineering have developed a compact and lightweight platform for conducting automated semen analysis using a lens-free on-chip microscope.


Semen analysis is an important and extensively routine for evaluating male fertility and preparing artificial insemination. Current approaches include manually counting sperm through an optical microscope, utilizing complex algorithms to analyze images recorded from microscopes or indirectly qualifying sperm concentration through electrical or chemical means. These approaches fall short of ideal because they are labor-intensive, prohibitively expensive or not sufficiently discriminating of sperm motility. Demand therefore exists for a system that is easy to use while sufficiently fast and accurate.


The innovation described here is a lightweight, compact and cost-effective platform for conducting automated semen analysis on a chip. The platform leverages a lens-free holographic on-chip microscope and software that is capable of accurately distinguishing and counting motile and immotile sperm.


Fertility testing for fertility clinics, personal fertility testing or veterinary medicine.


• Lightweight, compact and cost-effective
• Automated analysis requiring little manual effort

State Of Development

The method has been prototyped and successfully demonstrated.

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 8842901 09/23/2014 2011-044


Learn About UC TechAlerts - Save Searches and receive new technology matches


  • Ozcan, Aydogan

Other Information


semen analysis, male fertility, fertility, artificial insemination, sperm concentration, sperm count, sperm motility

Categorized As