UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree incoherent holographic microscope using a plasmonic aperture.
Lensfree imaging has gained interest due to the potential to eliminate bulky optical components and to develop on-chip microscope systems, which would be beneficial for microfluidic systems used in medical diagnostics and cytometry applications. A lightweight and compact, lensfree-imaging modality would also be a cheaper alternative to conventional lens-based microscopy, especially for telemedicine applications. Current imaging modalities that are compact, cost-effective, and easy to use either have poor performance or low resolution, limiting their practical use.
Researchers led by Professor Aydogan Ozcan have invented a novel lensless incoherent holographic microscope with a resolution of ~500 nm over a field of view (FOV) of ~5 mm2 and can achieve subcellular resolution over a large FOV of 24 mm2. This compact and lightweight microscope does not require any lenses, lasers, or other bulky optical and mechanical components and instead, utilizes a simple light emitting diode and a compact optoelectronic sensor-array.
|United States Of America||Issued Patent||9,202,835||12/01/2015||2009-454|
Lensfree, incoherent, holographic, lensless microscope, holographic microscope, nanosurface, plasmonics, medical diagnostics, cytometry, on-chip microscope