Triple Transgenic Mouse Model of Alzheimer's Disease

Technology Description

University of California, Irvine researchers have developed a novel transgenic mouse model that contains the three major genes that contribute to the hallmark pathological features of Alzheimer's disease. These mice are exceedingly valuable for therapeutic investigations and for basic research aimed at understanding the behavioral, physiological, molecular/cell biological, and pharmacological processes leading to dementia in an animal model. Even though these mice contain three transgenes, the mice essentially breed as readily as a "single" transgenic line, greatly facilitating the establishment and maintenance of an animal colony.

Patent Status