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Radioactive Bone Cement

The core innovation is a dosimetry-driven approach that determines the activity concentration of a radioisotope based on the distance between the cement surface and the target tissue, enabling predictable, volume‑independent radiation dosing.

Polymeric Benzopyrylium Chemistries for Peroxynitrite Detection in Disease

Brief description not available

SFK Covalent Protein Genetic Engineering Platform: Unlocking Potent Therapeutics for Undruggable Targets

Brief description not available

Rapid Diagnostic Platform for Stratifying Cancer Patients with Immunoresponsive ‘Cold’ Tumors via TGFß Signaling and DNA Damage Response

Brief description not available

A Fluorescent-Labeled Phage Display Platform: RAPID and BIAS Technologies Transform Antibody Discovery for Therapeutic Development

Brief description not available

Protein Engineering with Phosphorus Fluoride Exchange (PFEx): A Novel Click Chemistry Approach for Biotherapeutics and Proteomics

Brief description not available

Novel Molecular Glues Targeting 14-3-3/ER for Treatment-Resistant ER+ Breast Cancer

Brief description not available

Next-Generation CRISPR-Barcoded Organoid-Mouse Models for Prostate Cancer Drug Discovery and Immunotherapy Research

Brief description not available

RocASO: A Breakthrough Platform to Silence Undruggable RNA Targets and Transform Therapeutics

Brief description not available

Precision Oncology Diagnostic: Epithelial-to-Mesenchymal Transition Gene Signature Technology for Metastasis Prediction and Personalized Cancer Care

Brief description not available

Epipangi-Dx: A Cell-Free Dna Methylation Fingerprint For The Early Detection Ofgastrointestinal Cancers

A novel method for detecting, diagnosing, monitoring, and treating gastrointestinal cancers by analyzing DNA methylation levels in patient samples.

Cell Type-Selective, Potent Signaling Pathway Modulation Using A Guide-Effector Bispecific Design

Brief description not available

Manipulation Of Internalization Property Of Cell Surface Molecules Using A Guide-Effector Bispecific Design

Brief description not available

Immune Impact Of Cyclic STAT3 Decoy Therapy

Brief description not available

Covalent Chemical Inhibitors Of The Oncoprotein K-Ras (G12R)

Brief description not available

Discovery Of Kras G12c Inhibitor-Specific Antibodies For Oncogene-Specific Chemically-Directed Immune Targeting

Brief description not available

Collimated Compton Camera

Brief description not available

Induced Synthetic Intracellular Cytokine And Growth Factor Circuits For Cell Autonomous Control Of Cell Signaling, Proliferation, Survival And Cell State

Brief description not available

A Predictive ML Model For Cancer Early Relapse

Brief description not available

Methods Of Treating Stat1 Dependent Cancer

Brief description not available

Inhibitors Of P90 Rsk

Brief description not available

Autologous Irradiated Whole Cell Tumor Vaccines Lentivirally Engineered To Express Cd-80, Il-15 And Il-15 Receptor Alpha

Brief description not available

Identification Of Selective Regulators Of Oncogene Translation

Brief description not available

CAPTaINs: Capped And Protected Targeted Immunoproteasome N-End Degrons

CAPTaINs provide a novel, selective, and stable method for selective degradation of protein targets.

The Isolated Heparin-binding Domain (HBD) of VEGF165 and the Isolated D1 Domain of VEGFR2 (KDR)

Researchers at the University of California, Davis have developed recombinant fusion protein compositions that inhibit pathological angiogenesis by targeting VEGF165-KDR interactions to treat cancers and related diseases.

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