Researchers at the University of California, Davis have developed adjunctive therapies applicable to multiple types of infectious conditions. These therapies – derived from compounds found in natural herbs - also have potential prophylactic efficacy.
Increased human and veterinary antibiotic resistance has become a major global health concern. Researchers know that many species – including mammals – have genes that encode small peptides that possess broad-spectrum, anti-microbial properties effective against multiple types of pathogens.
Researchers at the University of California Davis have developed a strategy that applies compounds derived from natural herbs to upregulate the endogenous expression of antimicrobial peptides. These peptides then prove effective against bacterial, fungal and viral infections. This anti-microbial approach can be used as a topical medication, can be impregnated into contact lenses, deployed as a nebulizer for respiratory infections and offers new treatment options for chronic wounds caused by conditions such as diabetes and chronic venous ulcers.
Anti-microbial Resistance, Adjunctive Therapy, Natural Compounds, Immunity, Therapeutic