A new and novel 18F-fluordeoxyglycosylamine compound that may be used to image beta-amyloid plaques in the brain to help in the diagnosis of neurological diseases such as Alzheimer’s disease.
Brain amyloid plaques are one of the hallmark, pathological features of Alzheimer's Disease (AD) and maybe detected using Positron Emission Tomography (PET) scan images of the brain.
Researchers at the University of California, Irvine have developed a new 18F-fluordeoxyglycosylamine radiotracer that may be used to help diagnose AD by imaging beta-amyloid plaques in the brain.
|United States Of America||Issued Patent||9,546,193||01/17/2017||2014-266|
This radiotracer has been tested on tissue from AD patients and shown to bind to beta-amyloid plaques similar to 3H-PIB developed by the University of Pittsburgh.