4D Echo Particle Image Velocimetry Reconstruction of Cardiac Flows

Tech ID: 23382 / UC Case 2013-642-0

Brief Description

Echo Particle Image Velocimetry (PIV) is a non-invasive ultrasonic technique used to image blood flow in patients. Particles that may be used as flow tracers with PIV include currently FDA approved contrast agents.

Currently, 2D blood flow information obtained by echocardiography is widely used to diagnose cardiac dysfunction. While this 2D echocardiography method is useful, it does not provide sufficient accuracy for characterizing complex 3D flows in the heart. For example, it is difficult to accurately image flow patterns in the right heart or hearts of patients with congenital defects or quantify mitral regurgitation.

Researchers at the University of California, Irvine have developed a new method for multi-planar 3D reconstruction of 2D Echo Particle Image Velocimetry (PIV) data. This method may be used to image and assess blood flows from the heart chambers in real-time therefore allowing 4D imaging of blood flows in the heart.

Suggested uses

Improve clinical diagnosis of cardiac diseases, and patient specific modeling.

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 10,345,132 07/09/2019 2013-642


This imaging method has been tested in a pulsatile heart-flow simulator. It is now being tested in clinics.


Learn About UC TechAlerts - Save Searches and receive new technology matches

Other Information


Particle image velocimetry, Ultrasound, Echocardiography, Echocardiogram, Diagnosis, Cardiovascular diagnosis, Diagnostic tool, Diagnostic imaging, Medical imaging, 4D, 3D, three-dimensional, Velocity vector field, Velocity profile, Flow field, Flow sensitive, 4D Flow, 4D-Flow, Non-invasive, Portable, Inexpensive, Matrix array transducer, 3D matrix array transducer, Matrix array probe, 3D ultrasound probe, 3D ultrasound transducer

Categorized As