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Method and Apparatus for Movement Therapy Gaming System

Rehabilitation therapy, while an important tool for the long term recovery of patients affected by brain injury or disease, is expensive and requires one-on-one attention from a certified healthcare professional. UCI researchers have developed a computer-based system that provides arm movement therapy for patients. The system allows patients to independently practice hand and arm movements, improving therapeutic outcomes, while reducing hospital visits and cost for both patients and healthcare providers.

Flexible, Biocompatible Microfluidics-inspired Micro-reference Electrodes for Sensing Applications

Researchers at UCI have created miniaturized, flexible, biocompatible reference electrode with a streamline design capable of being used in a variety of different laboratory and clinical environments.

System For Fast Multi-Photon Imaging Using Spectrally Diffracted Excitation

UCLA researchers in the Department of Electrical Engineering have developed a new system for fast multi-photon imaging using spectrally diffracted excitation.

Array Atomic Force Microscopy Enabling Simultaneous Multi-point and Multi-modal Nanoscale Analyses

Nanoscale multipoint structure-function analysis is essential for deciphering the complexity of multiscale physical and biological systems. Atomic force microscopy (AFM) allows nanoscale structure-function imaging in various operating environments and can be integrated seamlessly with disparate probe-based sensing and manipulation technologies. However, conventional AFMs only permit sequential single-point analysis. Widespread adoption of array AFMs for simultaneous multi-point study is still challenging due to the intrinsic limitations of existing technological approaches.

Near-Zero Power Fully Integrated CMOS Temperature Sensor

With the planned proliferation of the Internet-of-Things, billions of power limited wireless sensing devices are expected to be sold worldwide.  Within that group is a large subset of applications in which temperature sensing will be important.  Needed for this application space are ultra-small and ultra-low-power temperature sensors. 

Low-noise Low-power ADC for Direct Biopotential Recording in Neuroscience Applications

High-density multi-channel neural recording is critical to driving advances in neuroscience and neuroengineering through increasing the spatial resolution and dynamic range of brain-machine interfaces.  Neural signal acquisition ICs have conventionally been designed composed of two distinct functional blocks per recording channel: a low-noise amplifier front-end (AFE), and an analog-digital converter (ADC).  Hybrid architectures utilizing oversampling ADCs with digital feedback have seen recent adoption due to their increased power and area efficiency. However, input dynamic range (DR) is still relatively limited due to aggressive supply voltage scaling and/or capacitive sampling noise.

Cloud- enabled Wireless pH Monitoring in Laboratory Sample Vials

A team of inventors at UCI have developed a miniaturized, wireless pH sensing system capable of monitoring the pH of laboratory samples in real-time with cloud-enabled connections for data collection. The sensor is designed to fit into the caps of standard sample vials, providing continuous measurements and eliminating the need to open vials during sensing.

Energy Radiator Using Strain-Mediated Spin Torque Nano-Oscillator (S-STNO)

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed an energy radiator based on a spin torque nano-oscillator that does not require the application of an external field.

Source Tracking Though Spectral Matching To Mass Spec Databases

Modern metabolomics, proteomics and natural product datasets have now reached into the millions of tandem mass (MS/MS) spectra. The rapidly growing size of these datasets precludes laborious manual data interpretation of all of the data. While MS/MS spectral library search approaches match spectra in an automated fashion, the limited size of available spectral libraries limits identification rates of datasets to single digit percentages. In addition, the sharing of experimental MS/MS data between researchers is not that common. What is needed is a way to organize both identified and unidentified spectra into structurally related molecular families that is searchable.

Selective Deposition Of Diamond In Thermal Vias

UCLA researchers in the Department of Materials Science & Engineering have developed a new method of diamond deposition in integrated circuit vias for thermal dissipation.

Secure Advanced Monitoring Systems

Maintaining secure networks is critical for large and high-value institutions, but providing technical staff with remote direct access to sensitive systems and real-time operational data can be vital to protecting value. For example, UC San Diego maintains highly-secure networks, yet there is a need to provide monitoring for freezer systems that contain priceless samples and materials that are often irreplaceable

Flavonol Profile as a Sun Exposure Assessor for Grapes

Researchers at the University of California, Davis have developed a solar radiation assessment method for grapes that uses a flavonol profile. This method can be done using either HPLC or through the computer processing of the absorption spectra of a purified flavonol extract via a purification kit.

Broadband Comb-Based Spectrum Sensing

Researchers at the UCLA Department of Electrical & Computer Engineering have developed a millimeter-wave spectrum analyzer that uses a non-linear fast switch to generate a broadband frequency comb local oscillator (LO) with a tunable repetition rate.

Scanning Terahertz Nanoscopy Probe

UCLA researchers in the Department of Electrical Engineering have developed a Scanning Terahertz Nanoscopy (STN) system with significantly improved detection sensitivity and spatial resolution.

A Bio-Impedance Measurement Technique Using Biphasic Current Stimulus Excitation for Implantable Stimulators

UCLA researchers from the Department of Bioengineering have developed a novel efficient, low-cost, low-power technique for measuring the bio-impedance at the electrode-tissue interface, which can be incorporated into implantable stimulators.

Hydrogel Thin Film-Based Dynamic Structural Color System for Sensing, Camouflage, and Adaptive Optics

UCLA researchers from the Department of Material Science and Engineering have developed a novel hydrogel color system that can be used for dynamic sensing, camouflage, and adaptive optics.

A Device For Continuous Focusing And Rotation Of Biological Cells And Its Application For High Throughput Electrorotation Flow Cytometer

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel device for high-throughput label-free analysis of cells.

Plasma Opening Switch

UCLA researchers in the Department of Physics have developed a plasma opening switch that enables quick diversion of multi-gigawatt pulses to a protective shunt circuit.

Nano Biosensing System

Metabolites can provide real-time information about the state of a person’s health. Devices that can detect metabolites are commercially available, but are unable to detect very low concentrations of metabolites. Researchers at UCI have developed surfaces that use nanosensors to detect much lower concentrations of such metabolites.

Membrane Insertion of Potential Sensing Nanorods

UCLA researchers in the Department of Chemistry have developed inorganic semiconductor nanosensors that measure membrane voltage.

Microfluidic Interfacial Magnetic Separation (MIMS)

UCLA researchers in the Department of Medicine and Bioengineering have developed a novel magnetic method for sorting cells.

In-Situ TEM Holder With STM Probe And Optical Fiber

Researchers at UCI have developed a fully integrated sample mount for the simultaneous high-resolution imaging and electronic and optical characterization of thin film devices.

New Method For Underwater Wireless Communication

Underwater communication presents many challenges in order to transmit data with large bandwidth and over long distance and/or over a wide area.  Indeed, water absorption, scattering and turbidity prevent radio waves to be used similarly as in air. Acoustic transmission has therefore been the standard technology for decades, but suffers from a very small bandwidth (less than 1 Mbps), whereas a video stream or conventional large data stream requires a bandwidth higher than 10Mbps.  Free Space Optical systems have been developed and tested underwater lately taking advantage of the development of lasers and LEDS with wavelengths around 500nm. In this range, water absorption is minimal and optical communication range could theoretically reach 150m with a bandwidth in the tens of Mbps. Large distance communication and correct alignment between the transmitter and the receiver remain however challenging.   UC Berkeley researchers have developed a new method for long-distance and/or wide­area underwater wireless communication using Autonomous Underwater Vehicles (AUVs) equipped with a Free Space Optical system allowing high bandwidth communication. The high stability and agility of the AUV allows to maintain a correct alignment between the receiver and the transmitter of two different AUVs keeping the data communication operational. 

Ultra-Dense Electrode-Based Brain Imaging System With High Spatial And Temporal Resolution

UCLA researchers in the Department of Bioengineering have developed a novel integrated brain imaging system that utilizes an ultra-dense electrode-based device. This system provides high resolution of functional brain images spatially and temporally.

Air Quality Monitoring Using Mobile Microscopy And Machine Learning

UCLA researchers have developed a novel method to monitor air quality using mobile microscopy and machine learning.

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