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Nano Biosensing System

Metabolites can provide real-time information about the state of a person’s health. Devices that can detect metabolites are commercially available, but are unable to detect very low concentrations of metabolites. Researchers at UCI have developed surfaces that use nanosensors to detect much lower concentrations of such metabolites.

Membrane Insertion of Potential Sensing Nanorods

UCLA researchers in the Department of Chemistry have developed inorganic semiconductor nanosensors that measure membrane voltage.

Microfluidic Interfacial Magnetic Separation (MIMS)

UCLA researchers in the Department of Medicine and Bioengineering have developed a novel magnetic method for sorting cells.

In-Situ TEM Holder With STM Probe And Optical Fiber

Researchers at UCI have developed a fully integrated sample mount for the simultaneous high-resolution imaging and electronic and optical characterization of thin film devices.

Ultra-Dense Electrode-Based Brain Imaging System With High Spatial And Temporal Resolution

UCLA researchers in the Department of Bioengineering have developed a novel integrated brain imaging system that utilizes an ultra-dense electrode-based device. This system provides high resolution of functional brain images spatially and temporally.

Air Quality Monitoring Using Mobile Microscopy And Machine Learning

UCLA researchers have developed a novel method to monitor air quality using mobile microscopy and machine learning.

Automatic Personal Daily Activity Tracking

Researchers at UCI have developed an entirely unobtrusive method for chronicling and analyzing an individual’s daily activities over time, which relies on tracking user activity via their smartphone. This technology has important applications in health and behavior monitoring, where it can be used to signal the early stages of various diseases and disorders.

Nondestructive System for Quantitative Evaluation of Cartilage Degradation and Regeneration

Researchers at the University of California, Davis, have developed a minimally invasive fluorescence based imaging system for the quantitative detection of cartilage health.

Simple All-in-One UV Waveguide Microscope with Illumination Sectioning for Surface Morphology and Fluorescence Imaging

Researchers at the University of California, Davis have developed an all-in-one microscope combining ultraviolet excitation light with a waveguide directly integrated onto a light microscope stage, capable of providing surface morphology and fluorescence information with minimal sample preparation.

Materials for Autonomous Tracking, Guiding, Modulating, and Harvesting of Energetic Emissions

UCLA researchers in the Department of Materials Science and Engineering have developed a novel photo-responsive polymer that can real-time detect, track, modulate, and harvest incident optical signals and a broad range of energetic emissions at high accuracy and fast response rate.

Adiabatic Dispersion-Managed Frequency Comb Generation

UCLA researchers have developed a novel methods and apparatus for the production of chip-scale dispersion-managed dissipative Kerr solitons in frequency combs, and their application in mode-locked and pulsed lasers.

Single-Pixel Optical Technologies For Instantly Quantifying Multicellular Response Profiles

UCLA researchers in the Department of Mechanical & Aerospace Engineering and the Department of Pathology & Lab Medicine have proposed a new platform technology to actuate and sense force propagation in real-time for large sheets of cells.

Mobile Phone Based Fluorescence Multi-Well Plate Reader

UCLA researchers have developed a novel mobile phone-based fluorescence multi-well plate reader.

Controlled 'One-Cell-One-Bead' Encapsulation in Droplets

Improving droplet encapsulation of a single-cell and single-bead to increase pharmacological assay throughput.

Accelerating palladium nanowire hydrogen sensors using engineered nanofiltration layers

Researchers at UCI have developed a method for enhancing existing hydrogen gas sensors, leading to as much as a 20-fold improvement in sensor response and recovery times.

At-Nozzle Injection of Agrochemicals

Researchers at the University of California, Davis have developed a direct, at-nozzle system for directly mixing and dispensing a carrier fluid with additives.

Novel Sensor to Transduce and Digitalize Temperature Utilizing Near-Zero-Power Levels

Temperature sensors are routinely found in devices used to monitor the environment, the human body, industrial equipment, and beyond. In many such applications, the energy available from batteries or the power available from energy harvesters is extremely limited, thus the power consumption of sensing should be minimized in order to maximize operational lifetime.

Novel Anti-Bacterial, Anti-Fungal Nanopillared Surface

Medical devices are susceptible to contamination by harmful microbes, such as bacteria and fungi, which form biofilms on device surfaces. These biofilms are often resistant to antibiotics and other current treatments, resulting in over 2 million people per year suffering from diseases related to these contaminating microbes. Death rates for many of these diseases are high, often exceeding 50%. Researchers at UCI have developed a novel anti-bacterial and anti-fungal biocomposite that incorporates a nanopillared surface structure that can be applied as a coating to medical devices.

Drift-Free, Self-Calibrated Interrogation Method For Electrochemical Sensors Based On Electron Transfer Kinetics

A new method using chronoamperometry in place of voltammetry to obtain data from electrochemical sensors, including electrochemical biosensors.

Microfluidics Device For Digestion Of Tissues Into Cellular Suspension

A microfluidic device that separates single cells from whole tissue in a rapid and gentle manner using hydrodynamic fluid flow. The separated single cell suspensions can then be used in tissue engineering applications, regenerative medicine and the study of cancer.

Scanning Method For Uniform, Normal-Incidence Imaging Of Spherical Surface With A Single Beam

UCLA researchers have created a method that achieves uniform normal-incident illumination of a spherical surface by first projecting the sphere onto a Cartesian plane and then raster scanning it using an illuminating beam. This allows the scanned object, the illumination source, and the detector to remain stationary.

High-Throughput And Label-Free Single Nanoparticle Sizing Based On Time-Resolved On-Chip Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a rapid, low-cost, and label-free methodology for nanoparticle sizing.

Microscopic Color Imaging And Calibration

UCLA researchers in the Department of Electrical Engineering have developed a color calibration method for lens-free and mobile-phone microscopy images allowing for high resolution and accurate color reproduction.

Wide-Field Imaging Of Birefringent Crystals In Synovial Fluid Using Lens-Free Polarized Microscopy For Crystal Arthropathy Diagnosis

UCLA researchers in the Department of Electrical Engineering have developed a new diagnostic tool for arthropathic diseases, such as gout.

Single Molecule Imaging and Sizing of DNA on a Cell Phone

UCLA researchers in the Department of Electrical Engineering have developed a light-weight and cost-effective fluorescence microscope installed on a cell phone.

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