Growth Factor Sequestering and Presenting Hydrogels

Tech ID: 22482 / UC Case 2012-118-0

Patent Status

Country Type Number Dated Case
United States Of America Published Application 20150352156 12/10/2015 2012-118
European Patent Office Published Application 2012-118
 

Brief Description


The encapsulation of stem cells in a hydrogel substrate provides a promising future in biomedical applications. However, communications between hydrogels and stem cells is complicated, for example, factors such as porosity, different polymer types, stiffness, compatibility and degradation will lead to stem cell survival or death. Hydrogels mimic the three-dimensional extracellular matrix to provide a friendly environment for stem cells.

 

UC Berkeley researchers have developed hydrogel cell matrices for the support, growth, and differentiation of a stem cell or progenitor cell and methods for making such hydrogel cell matrices.

Suggested uses


  • Cardiac tissue engineering
  • Reinforcement of scleral tissue
  • Fat tissue engineering
  • Wound healing matrix
  • Drug delivery 

 

Advantages


  • Increases survival and engraftment of transplanted stem cells
  • Hydrogel has tuneable release kinetics and degradation rate

 

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Other Information

Keywords

Hydrogel, tissue engineering, stem cell, polymer, biocompatible, biodegradable

Categorized As