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Antimicrobial and Osteoinductive Hydrogel for Dental Applications

UCLA researchers in the Department of Chemical & Biomolecular Engineering developed osteoinductive and antimicrobial hydrogel adhesives for dental applications.

Homogeneous Freestanding Luminescent Perovskite Organogel with Superior Water Stability

UCLA researchers in the Department of Materials Science and Engineering have developed a perovskite-embedded organogel with superior water stability and versatile design and mechanical properties.

System And Method For Producing Polyhydroxyalkanoates From Organic Waste

Researchers at the University of California, Davis have developed an efficient method for producing polyhydroxyalkanoates (PHA) from organic waste using a halophilic microorganism.

Gelatin Methacryloyl Based Microneedle

UCLA researchers in the Department of Bioengineering have developed gelatin methacryloyl microneedles (GelMA MN) for minimally invasive, sustained transdermal drug delivery.

Development Of Organ-Preservation Solution Based On O2 Releasing Particles

UCLA researchers in the Departments of Bioengineering, Radiology, and Chemical and Biomolecular Engineering have developed a novel oxygen-generating material for promoting the viability of cells.

Use Of Non-Ionic Copolypeptide Hydrogels For Cell Suspension And Cell And Molecule Delivery

UCLA researchers in the Departments of Bioengineering, Chemistry and Biochemistry, and Neurobiology have developed novel copolypeptide hydrogel formulations for the delivery of cells and molecules to locations throughout the body, including the central nervous system.

New Polymer Additive that De-adheres Upon Light Exposure

Researchers at UCR have developed a new additive that may be added to adhesives.  When the UCR compound additive and polymer adhesive are exposed to visible light, this significantly weakens the adhesive bond.  The additive and adhesive may be mixed at room temperature and then it may be applied to surfaces to adhere them together.  Upon exposure to light the surfaces de-adhere. Fig. a shows solid dye particles encapsulated between 2 glass slides which are glued together by the UCR additive incorporated into a polystyrene film. 532 nm irradiation causes the polystyrene adhesion to fail and the bottom slide to drop off in Fig. b, releasing the red dye into the surrounding water.  

Material For Thermal Regulation

Researchers at UCI have developed a lightweight, flexible thermal material that, due to the extent that it is stretched, allows for tunable control of heat flow.

Flexible, Biocompatible Microfluidics-inspired Micro-reference Electrodes for Sensing Applications

Researchers at UCI have created miniaturized, flexible, biocompatible reference electrode with a streamline design capable of being used in a variety of different laboratory and clinical environments.

Microporous membranes for the separation of enantiomers

Current methods used to separate racemic compounds on a large scale have limitations in cost, energy efficiency, and discontinuous processing. UCI researchers have synthesized a membrane made of chiral porous polymers that can separate enantiomers from racemic mixtures through continuous processing.

Pressure Sensitive Fabrics

Piezoelectric sensors have long existed to monitor applied pressures between two objects. In large applications with malleable substrates or where low cost is key, individual piezoelectric sensors are not practical. A variety of applications exist where monitoring the pressure being applied to a soft surface would providing meaningful insights into the system or subject under observation. For instance, in a long-term care setting where patients need to be monitored for pressure ulcers, a bedding material that could sense the pressure points between a person’s body and the mattress could alert care givers that an adjustment in body position is warranted. Likewise, in a sports training application, a pressure sensitive boxing ring canvas could track a boxer’s footwork, or punching power and hand speed if applied to the inside of a punching bag.   Pressure sensitive soft toys could also benefit from feedback that might differ when a child scratches behind their stuffed animal’s ears vs. rubbing its belly.  To achieve discrete sensing in these applications, a low cost bulk sensing system is needed.

Cephalopod-Inspired Adaptive Infrared Camouflage Materials and Systems

This technology is a new class of materials capable of thermal regulation and active camouflage. These cephalopod-inspired materials, configurable to different geometries, can be used in many sectors, ranging from consumer to industrial to military applications.

Metabolite-Responsive Hybrid Biomaterials

Researchers have developed a “smart” biomaterial for drug delivery systems capable of responding to signature cancer metabolite concentrations in tumor environments. This response triggers the release of encapsulated drugs at a specific tumor target.

Trehalose Hydrogels For Stabilization And Delivery Of Proteins

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel trehalose hydrogel to help stabilize proteins for drug delivery.

One Step Process of Forming Complex Coacervation During Spray Drying

Researchers at the University of California, Davis have developed a formation of complex coacervate microparticles by spray drying.

Preparation Of Functionalized Polypeptides, Peptides, And Proteins By Alkylation Of Thioether Groups

UCLA researchers in the Departments of Chemistry, Physics, and Bioengineering, led by Dr. Tim Deming of the Bioengineering Department, have developed new methods for adding different functional groups on polypeptides.  The UCLA researchers have used this method to create a platform to create and modify nanoscale vesicles and hydrogels for use in nanoscale drug delivery particles, injectable drug depots, imaging and detection, industrial biomaterials, and wound management.

Amphiphilic Derivatives Of Thioether Containing Block Copolypeptides

UCLA researchers in the Department of Bioengineering have developed a new method to generate amphiphilic block copolypeptides.

Chemoselective Side-Chain Modifications Of Methionine-Containing Elastin-Like Polypeptides

UCLA researchers in the Department of Bioengineering and Department of Chemistry & Biochemistry have developed a novel method for the introduction of various functional groups onto recombinant elastin-like polypeptides (ELPs), creating new compositions of ELPs that may be used for medical therapeutic or diagnostic applications.

Development Of Surface Enhanced Graphene Oxide For Ubiquitous Antibacterial Coatings

UCLA researchers in the Department of Medicine have developed a novel graphene oxide (GO) based material with significantly enhanced antibacterial effects with maximized surface display of carbon radicals.

Thaw Gelation Process for Encapsulating Cell Spheroids

Researchers at the University of California Davis have developed a thaw gelation process for the formation of cell spheroids within a hydrogel shell.

Micro- and Nanocomposite Support Structures for Reverse Osmosis Thin Film Membranes

UCLA researchers in the Department of Civil and Environmental Engineering have invented a novel nanofiltration (NF) and reverse osmosis (RO) composite membrane for water desalination applications.

Novel Multi-Scale Pre-Assembled Phases of Matter

UCLA researchers from the Departments of Chemistry and Physics have developed a novel method for creating multi-scale pre-assembled phases of matter with customizable symmetries, topologies, and degrees of order and disorder.

Robust, Ultra-Flexible, Micro-Encoded Ferromagnetic Tape for Bioseparation and Assembly

Researchers at the UCLA Department of Bioengineering have developed methods to embed electroplated magnetic materials within elastomeric materials and use these flexible magnetic hybrid materials for biological applications.

3D Scaffolds For Mesoderm Differentiation

Researchers led by Benjamin Wu from the Departments of Bioengineering and Pathology & Laboratory Medicine have developed an implantable scaffolding that can create hematopoietic stem cells from pluripotent stem cells in vivo.

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