Growth Factor Sequestering and Presenting Hydrogels

Tech ID: 22482 / UC Case 2012-118-0

Patent Status

Country Type Number Dated Case
European Patent Office Issued Patent 2946011 04/17/2019 2012-118
United States Of America Issued Patent 9,827,272 11/28/2017 2012-118
Germany Published Application 2012-118
United Kingdom Published Application 2012-118

Brief Description

The encapsulation of stem cells in a hydrogel substrate provides a promising future in biomedical applications. However, communications between hydrogels and stem cells is complicated, for example, factors such as porosity, different polymer types, stiffness, compatibility and degradation will lead to stem cell survival or death. Hydrogels mimic the three-dimensional extracellular matrix to provide a friendly environment for stem cells.


UC Berkeley researchers have developed hydrogel cell matrices for the support, growth, and differentiation of a stem cell or progenitor cell and methods for making such hydrogel cell matrices.

Suggested uses

  • Cardiac tissue engineering
  • Reinforcement of scleral tissue
  • Fat tissue engineering
  • Wound healing matrix
  • Drug delivery 



  • Increases survival and engraftment of transplanted stem cells
  • Hydrogel has tuneable release kinetics and degradation rate


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Other Information


Hydrogel, tissue engineering, stem cell, polymer, biocompatible, biodegradable

Categorized As