A novel protoacoustic imaging method and apparatus providing affordable, real-time verification of proton range and quantification of radiation dose during proton therapy to improve treatment precision and patient outcomes.
This technology utilizes the protoacoustic effect—acoustic emissions generated by pulsed proton beams—to produce in vivo, real-time imaging of the Bragg peak during proton radiotherapy. By integrating an ultrasound transducer array with proprietary tracking and reconstruction algorithms, it enables precise localization of proton dose deposition with sub-millimeter accuracy. This capability significantly reduces proton beam range uncertainties, allowing for targeted cancer treatment with minimized damage to healthy tissues. The system is adaptable to clinical proton therapy machines without vendor dependencies and includes hardware and software optimized for acquiring, processing, and reconstructing protoacoustic signals into 3D dose maps.
Country | Type | Number | Dated | Case |
Patent Cooperation Treaty | Reference for National Filings | WO 2023/278627 | 01/25/2023 | 2021-964 |
Patent Pending
Proton Therapy, Medical Device, Protoacoustic Imaging, Proton Induced Acoustic Imaging, In Vivo Dosimetry, 4D Dosimetry, Bragg Peak Localization, Radiation Oncology