UCLA researchers in the Department of Radiation Oncology have developed a novel method to gate radiotherapy using low frame rate MRI sequences to reduce damage to adjacent tissues during radiotherapy.
Taking respiratory movements into account during radiotherapy has always been a major concern in radiotherapy treatments that are affected by lung movement (e.g. thoracic or abdominal cancer). Currently, a common method for gating radiotherapy to prevent healthy tissue damage is by using MRI sequences. While MRI can provide better visualization of the tumor, some MRI sequences (e.g. T2 weighted sequences) are too slow to account correctly for the human breathing cycle. A method to improve the accuracy of MRI-guided radiotherapy would greatly improve radiotherapy.
Researchers at UCLA have developed a novel method to use low frame rate MRI sequences for radiotherapy gating. The technology enables accurate modeling of patient-specific respiratory motion from continuously acquired MRI images. The method is able to predict respiratory motions with high accuracy, enabling correct gating of radiotherapy for a more precise and safer treatment.
|Patent Cooperation Treaty||Published Application||WO2019027947||02/07/2019||2017-839|
Additional Patents Pending
Radiotherapy, Magnetic resonance imaging, MRI, Gate radiotherapy, Breathing motion model, Respiratory model, Tumor visualization