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Method for the detection of specific cells in bodily fluids with a small fluorescent probe
Using standard cellular biology techniques, researchers at UCI have developed a method for detecting the cellular components of blood easily, cheaply, and quickly with accurate quantification using fluorescence techniques.
Novel Protease for Oncology and Inflammatory Diseases
The technology is a novel protease that reduces the ability of cells to respond to the inflammatory cytokine Tumor Necrosis Factor (TNF). High TNF levels have been linked to rheumatoid arthritis, Crohn’s disease and many types of cancers.
Endoscopic ultrasound-guided fine needle injection
Endoscopic ultrasound-guided Fine Needle Aspiration (EUG-FNA) is a method by which tissue biospies are collected using a needle tip guided by real-time ultrasound imaging. UCI physicians propose a novel utility for EUS-FNA with enclosed fine needles that would allow the sterile injection of dyes, drugs and therapeutics to specific anatomical sites.
4D-seq: Single Cell RNA-sequencing with in situ Spatiotemporal Information
To develop a novel imaging-based single cell RNA-sequencing (scRNA-Seq) platform that allows capturing of spatiotemporal information and cellular behavior of the sequenced cells within tissue.
Potassium Channel Inhibitor for Autoimmune Disease Therapy
This invention is an analog of a naturally occurring potassium channel inhibitor. This potassium channel inhibitor has the potential to provide a great benefit to patients that suffer from autoimmune diseases.
Microscale Device and Method for Purification of Radiopharmaceuticals
UCLA researchers from the Departments of Molecular & Medical Pharmacology and Bioengineering have developed a novel method for the purification of radiopharmaceuticals for the on-demand production of positron emission tomography (PET) tracers.
Very-Small-Nuclear Circulating Tumor Cell (vsnCTC) as a Diagnostic Biomarker of Visceral Metastasis in Advanced Prostate Cancer
UCLA researchers in the Department of Molecular and Medical Pharmacology have identified a novel biomarker that can be used to diagnose prostate cancer patients for the presence of visceral metastasis with 54% sensitivity and 100% specificity.
Microbiome-Based Intervention For Intrauterine Growth Restriction
UCLA researchers in the Department of Integrative Biology and Physiology have identified one of the underlying causes of intrauterine growth restriction, which may be treated with microbiome-based therapeutics.