The LaserPack is an easily manufacturable solution for liquid storage in point-of-care devices that is low-cost, has dimensional variability, and is reproducible, while also serving as a valve for liquid access in microfluidic devices. Current liquid storage techniques rely on lyophilization, or freeze-drying, to minimize occupied space, but lyophilization is not applicable to all liquid reagents nor is it optimal for some biological components of point-of-care devices.

The California Lighting Technology Center at UC Davis in collaboration with the Center for Mind and Brain have developed a novel lighting technology approach for stress recovery and stress mitigation.

Stress and loneliness are biologically toxic factors with adverse effects on mental and physical health. The 2018 Gallup World Poll found a 25%–40% increase in stress, worry, and anger in the US from 2008 to 2018. Loneliness is associated with considerable distress, and older adults are vulnerable to loneliness due to losses, physical decline, and social isolation. The COVID-19 pandemic led to increased social isolation, though some older adults with higher levels of resilience and wisdom faced the pandemic with greater fortitude than younger adults.Aging is associated with numerous stressors that negatively impact older adults’ well-being. Resilience improves ability to cope with stressors and can be enhanced in older adults. Senior housing communities are promising settings to deliver positive psychiatry interventions due to rising resident populations and potential impact of delivering interventions directly in the community. 

Researchers at the University of California, Davis have developed agents made from terpenoids and salicylates that can be used as anesthetics in human and non-human animals, as well as environmentally friendly euthanasia agents in food-producing animals.

Researchers at the University of California, Davis have developed a customizable polysaccharide that can be added to nanoparticles to reduce their rejection by the human immune system.

Researchers at the University of California, Davis have developed high potency and selective peptide inhibitors that act as a non-addictive analgesic for relief of chronic and/or severe pain in humans.

Researchers at the University of California, Davis have developed a method of treating or mitigating seizure, treating epilepsy, as well as a method of reducing the frequency of seizures, using cannabigerol or dihydrocannabigerol and analogs thereof.

Researchers at the University of California, Davis, have developed a novel approach to treat hearing-related disorders with a new type of psychoplastogen that can increase the synapse density in the ear, correlating with hearing ability.

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A researcher at the University of California, Davis has developed a safety scalpel for mitigating the challenges associated with the removal of certain types of percutaneous implants, such as gastrostomy tubes having difficult to reduce anchoring elements.

Researchers at the University of California, Davis have developed a surgical device to facilitate vascular anastomosis procedures with enhanced ease and speed.

Researchers at the University of California, Davis have developed de novo positive allosteric modulators (PAMs) that bind to TRPV1 proteins involved with pain-sensing in order to provide analgesic effects.

Contact force is a natural way for humans to interact with the physical world around us. However, most of our interactions with the digital world are largely based on a simple binary sense of touch (contact or no contact). Similarly, when interacting with robots to perform complex tasks, such as surgery, we need to acquire the rich force information and contact location, to aid in the task. To address these issues, researchers at UC San Diego have developed WiForce, which is a ‘wireless’ sensor that can be attached to an object or robot, like a sticker. WiForce’s sensor transduces force magnitude and location into phase changes of an incident RF signal, which is reflected back to enable measurement of force and contact location.

Researchers at the University of California, Davis have developed a method of estimating blood plasma water content using nuclear magnetic resonance (NMR) relaxometry.

Researchers at the University of California, Davis have developed a device that allows needles to be reliably and easily bent to a range of specified and reproducible angles. The device also enables protection of the needle tip and the maintenance of needle sterility during bending.

Researchers at the University of California, Davis have developed machine learning models to enhance the accessibility and accuracy of acute kidney injury (AKI) testing.

This technology utilizes inter-subject measurement of brain activity for the purpose of matching individuals. In particular, the invention measures the similarity and differences in neural activity patterns between interacting individuals (either in person or online) as a signature measurement for their matching capabilities. Relevant applications can be in the world of human resources (e.g., building collaborative teams), patient-therapist matching and others. The application relies on the utilization of both custom and commercial devices for measuring brain activity.

Researchers at the University of California, Davis have developed a programmable machine that shakes and repeatedly inverts large numbers of small containers - such as vials and flasks – in order to mix high-viscosity fluids.

UCI researchers have developed a novel transcatheter pulmonary valve (TPV) that addresses the current lack of options for children with progressive pulmonary valve regurgitation (PVR), which may lead to right ventricular (RV) dysfunction and failure. This TPV allows for implantation into patients of a younger age, preventing the progression of PVR and the RV issues that follow, and can also expand to accommodate the need for a larger pulmonary valve as the patient grows.

Researchers at the University of California, Davis have developed a gyramide antibiotic which is effective against Gram-negative and fluoroquinolones (FQs) resistant bacteria.

Dural tear is a frequent and costly complication of spinal surgery, which can cause cerebrospinal fluid (CSF) leakage, triggering additional, serious post-operative difficulties. Researchers at UC Irvine have developed a new method and device to mitigate dural tears in a rapid, safe, and water-tight manner

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The inventor has developed systems and methods for performing continuous 3D roll-based additive manufacturing. This invention is distinct from roll-based micro/nanomanufacturing methods such as imprint lithography, gravure printing, and photo-roll lithography because it enables production of high aspect ratio reentrant features and voids in a single step that are difficult or even impossible with the existing methods.

The inventor has developed novel algorithms and metrology methodologies, including real-time in-situ imaging of part formation, in computed axial lithography printing (CALP). CALP is a form of continuous 3D roll-based additive manufacturing which is distinct from roll-based micro/nanomanufacturing methods such as imprint lithography, gravure printing, and photo-roll lithography because it enables production of high aspect ratio reentrant features and voids in a single step that are difficult or even impossible with the existing methods.

Researchers at UCI have developed a novel medical device for use in transcatheter heart valve replacement surgeries. The device provides physicians with more careful control of the catheter insertion, minimizing complications and adverse effects.