Changing diets and lifestyles are causing dramatic increases in painful kidney stones. Tastes for high-salt processed foods, high-sugar foods and drinks, and poor hydration are all causes. It is estimated that 10-20% of the population will develop a kidney stone, resulting in extreme pain, which may require surgical intervention. Alongside direct medical procedures, patients are often given potassium citrate pills as an adjunct therapy, but these are poorly-tolerated due to gastrointestinal side effects and large size of the pills, all of which decrease patient compliance. These current formulations require a twice-a-day dosing regimen, which only exacerbates the compliance problem. However, beyond these citrate pills, sadly few effective medical alternatives exist. To remedy this problem, UC San Diego physicians have recently developed a neutraceutical formulation, specifically designed to comprise precise balance of bioactives within a well-tolerated functional food, supporting the targeted relief of kidney stones.