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A Method To Determine Cause Of A Cardiac Arrest And Provide Cause-Specific Decision Support In Real-Time Using Continuous Electrocardiography

Researchers led by Duc Hong Do from the Department of Cardiology at UCLA have developed an algorithm to detect the cause of cardiac arrest in a hospital setting.

Generic Method for Controlled Assembly of Molecules

Researchers at the University of California, Davis, in collaboration with researchers at IBM, have developed a widely applicable method to assemble molecules regardless of their intrinsic self-assembly properties.

A New Human-Monitor Interface For Interpreting Clinical Images

UCLA researchers in the Department of Radiological Sciences have invented a novel interactive tool that can rapidly focus and zoom on a large number of images using eye tracking technology.

Nanoparticles For Specific Detection And Killing of Pathogenic Bacteria

UCLA researchers in the Department of Chemistry and Biochemistry and Department of Medicine have developed novel functionalized mesoporous silica nanoparticles that can specifically identify pathogenic bacteria and deliver on-target drug treatments.

Dicom/Pacs Compression Techniques

Researchers led by Xiao Hu from the Department of Surgery at UCLA have created a novel and convenient way to compress and query medical images from a PACS system.

Scanning Terahertz Nanoscopy Probe

UCLA researchers in the Department of Electrical Engineering have developed a Scanning Terahertz Nanoscopy (STN) system with significantly improved detection sensitivity and spatial resolution.

Equally Sloped (Pseudopolar) Tomography With Applications To Biological And Medical Imaging

UCLA researchers in the Department of Physics and Astronomy and the California NanoSystems Institute have developed a new tomographic imagine technique providing higher spatial resolution at a lower radiation dose.

Load-Induced Frequency-Shift-Keying: A New Modulation Scheme That Enables Simultaneous Near-Field Wireless Power And Data Transmission Through A Single Set of Inductive Coils

UCLA researchers in the Department of Electrical Engineering have developed the first modulation system that allows simultaneous wireless power and data transmission through a single pair of inductive coils.

Immersive Virtual Reality To Manage Pain

Researchers led by Mark Cohen from the Department of Psychiatry at UCLA have developed a virtual reality-based therapy to manage chronic pain.

Ultrafast Differential Interference Contrast Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a novel instrument that can image unstained transparent objects with high speeds.

The Bic Inhibitor Of Cry-Cry And Cry-Cib Oligomerization/ Clustering

UCLA researchers in the Department of Molecular, Cell, and Developmental Biology have discovered two Arabidopsis proteins, BIC1 and BIC2, that are capable of inhibiting light-dependent dimerization of cryptochrome (CRY) molecules. These BICs can be used as an improved drug screening platform through controlled, titratable, label-free and reversible protein – protein interactions.

A High Throughput Biochemical Fluorometric Method For Measuring HDL Redox Activity

UCLA researchers in the Department of Medicine have developed a method of screening for the functional properties of high-density lipoprotein (HDL) in the blood that may serve as a more accurate risk indicator of cardiovascular disease.

A Device, Methodology And System For Monitoring, Classifying And Encouraging Activity

UCLA researchers in the Department of Computer Science have developed a new technology to fight the growing obesity epidemic by encouraging exercise.

Inducible N-Degron Mediated Haploid Induction

Researchers at the University of California, Davis have developed a method of cell-specific degradation of centromeric proteins to induce haploid.

Small Molecules That Facilitate Exon Skipping

UCLA researchers in the Departments of Microbiology, Immunology, and Molecular Genetics, and Human Genetics have discovered a novel small molecule therapy that facilitates treatment of Duchene Muscular Dystrophy.

A Bio-Impedance Measurement Technique Using Biphasic Current Stimulus Excitation for Implantable Stimulators

UCLA researchers from the Department of Bioengineering have developed a novel efficient, low-cost, low-power technique for measuring the bio-impedance at the electrode-tissue interface, which can be incorporated into implantable stimulators.

Lipid Bilayer Formation Using Sessile Droplets

UCLA researchers in the Department of Bioengineering have developed a method to form a biologically functional lipid bilayer in a high-throughput and automated fashion.

3D Population Maps for Noninvasively Identifying Phenotypes and Pathologies in Individual Patients

UCLA researchers in the Department of Radiological Sciences have developed a novel computation system that uses large imaging datasets to aid in clinical diagnosis and prognosis.

3D Scaffolds For Mesoderm Differentiation

Researchers led by Benjamin Wu from the Departments of Bioengineering and Pathology & Laboratory Medicine have developed an implantable scaffolding that can create hematopoietic stem cells from pluripotent stem cells in vivo.

Bioengineered Thymic Aggregates For Implantation

Researchers led by Gay Crooks from the Department of Pathology and Laboratory Medicine at UCLA have bioengineered a thymus implant to treat immune diseases.

Improved HEV Nanoparticles for Oral Delivery

Researchers at the University of California, Davis have engineered a functionalized Hepatitis E Niral Nanoparticles (HEVNP) with gold-nanoclusters, enhancing its stability and making it highly biologically accessible, non-toxic, and suitable for oral delivery.

Synaptic Resistor With Signal Processing, Memory, And Learning Functions

Researchers led by Yong Chen from the Department of Mechanical and Aerospace Engineering have developed an artificial synapse for neuromorphic chips that have integrated logic, memory, and learning capabilities.

Assay for Oligonucleotides in Serum Without Extraction or RT-PCR

Prof. Ameae Walker’s laboratory at the University of California, Riverside (UCR) has developed an assay to quantify oligos in sub-picomole amounts without the need for sample purification and amplification. This new competitive assay is called an ELOHA (Enzyme-Linked Oligonucleotide Hybridization Assay). The method is illustrated in Fig. 1, below.  Capture Oligos that are to hybridize with an oligo to be measured are covalently linked to a plate (1), a Detection Oligo, with the same sequence as the oligo to be measured, has a conjugated label, such as horseradish peroxidase or biotin.  The Detection Oligo then competes with the oligo of interest for binding to the Capture Oligo (2).  Once the hybridization is complete, the unbound oligos are washed away (3).  A colorimetric readout is produced (4) to inversely quantify the oligo of interest.  Fig. 1 Schematic of the ELOHA assay Fig. 2 shows the use of an ELOHA for amounts of Antimaia in mouse serum. Antimaia is a splice modulating oligomer therapy for breast cancer developed in the UCR lab of Prof. Walker.  

Flexible And Stretchable Interconnects For Flexible Systems And Flextrate(Tm)

Researchers led by Professor Subramanian Iyer from the Department of Electrical Engineering at UCLA have developed a novel fabrication technique to create stretchable electronics.

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