Artificial Nitrogenase (Artn2ase) Enzymes For Biocatalytic Reduction Of N2 Into Ammonia

Tech ID: 34175 / UC Case 2024-9C0-0

Brief Description

A revolutionary enzyme technology for ambient temperature and pressure ammonia synthesis from dinitrogen gas.

Full Description

Artificial Nitrogenase (ArtN₂ase) enzymes are a groundbreaking class of computationally engineered proteins that catalyze the conversion of dinitrogen (N₂) to ammonia (NH₃) under ambient conditions. These enzymes incorporate natural or synthetic cofactors to mimic the nitrogenase enzyme's functionality. This innovation offers a sustainable and decentralized alternative to the traditional Haber-Bosch process for ammonia synthesis, operating without the need for harsh reaction conditions or fossil fuel-derived inputs.

Suggested uses

  • Decentralized and sustainable ammonia production for fertilizers and chemicals. 
  • Fertilizer manufacturing tailored for off-grid or resource-constrained regions. 
  • Green hydrogenation processes and nitrogen-transfer catalysis. 
  • Biomanufacturing platforms for carbon-neutral chemical synthesis. 
  • Research in synthetic biology and advanced protein engineering.

Advantages

  • Catalyzes ammonia synthesis at room temperature and atmospheric pressure. 
  • Eliminates the need for hydrogen gas, high temperatures, or high pressures. 
  • Reduces carbon emissions associated with traditional nitrogen fixation processes. 
  • Modular design facilitates adaptation to various nitrogen-transfer and hydrogenation reactions. 
  • Integrates computational design and synthetic chemistry for unprecedented control over enzyme functionality

Patent Status

Patent Pending

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