Artificial Nitrogenase (Artn2ase) Enzymes For Biocatalytic Reduction Of N2 Into Ammonia
Tech ID: 34175 / UC Case 2024-9C0-0
Brief Description
A revolutionary enzyme technology for ambient temperature and pressure ammonia synthesis from dinitrogen gas.
Full Description
Artificial Nitrogenase (ArtN₂ase) enzymes are a groundbreaking class of computationally engineered proteins that catalyze the conversion of dinitrogen (N₂) to ammonia (NH₃) under ambient conditions. These enzymes incorporate natural or synthetic cofactors to mimic the nitrogenase enzyme's functionality. This innovation offers a sustainable and decentralized alternative to the traditional Haber-Bosch process for ammonia synthesis, operating without the need for harsh reaction conditions or fossil fuel-derived inputs.
Suggested uses
- Decentralized and sustainable ammonia production for fertilizers and chemicals.
- Fertilizer manufacturing tailored for off-grid or resource-constrained regions.
- Green hydrogenation processes and nitrogen-transfer catalysis.
- Biomanufacturing platforms for carbon-neutral chemical synthesis.
- Research in synthetic biology and advanced protein engineering.
Advantages
- Catalyzes ammonia synthesis at room temperature and atmospheric pressure.
- Eliminates the need for hydrogen gas, high temperatures, or high pressures.
- Reduces carbon emissions associated with traditional nitrogen fixation processes.
- Modular design facilitates adaptation to various nitrogen-transfer and hydrogenation reactions.
- Integrates computational design and synthetic chemistry for unprecedented control over enzyme functionality
Patent Status
Patent Pending