Embryo Viability Assessment System Using Phasor Fluorescence Lifetime Imaging Microscopy

Brief Description

A non-invasive imaging system utilizing fluorescence lifetime microscopy and Fourier-transformed phasor analysis to objectively determine embryo viability.

Full Description

• Non-invasive and label-free embryo assessment method 
• Quantitative and objective analysis reducing human subjectivity 
• Faster evaluation compatible with clinical IVF timeframes 
• Minimized photodamage through two-photon excitation 
• Deeper imaging with high-resolution fluorescence lifetime data 
• Automated calculation of viability index from intrinsic metabolic signals 
• Reduces reliance on labor-intensive morphological inspection

Suggested uses

• In vitro fertilization (IVF) clinics for human assisted reproduction 
• Animal breeding facilities seeking enhanced embryo selection 
• Research institutions studying embryo development and metabolism 
• Development of advanced fertility diagnostic and monitoring tools 
• Integration into ART workflows to enable single embryo transfer protocols

Advantages

Non-invasive and label-free embryo assessment method Quantitative and objective analysis reducing human subjectivity Faster evaluation compatible with clinical IVF timeframes Minimized photodamage through two-photon excitation Deeper imaging with high-resolution fluorescence lifetime data Automated calculation of viability index from intrinsic metabolic signals Reduces reliance on labor-intensive morphological inspection

Patent Status