Cannabigerol (CBG) In The Treatment Of Seizures And Epilepsy

Tech ID: 32966 / UC Case 2022-512-0

Abstract

Researchers at the University of California, Davis have developed a method of treating or mitigating seizure, treating epilepsy, as well as a method of reducing the frequency of seizures, using cannabigerol or dihydrocannabigerol and analogs thereof.

Full Description

Cannabidiol (CBD), a biologically active constituent of the cannabis (hemp) plant, has been approved for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, and tuberoussclerosis complex. Using a standard model in the identification of antiseizure agents, CBD has been shown to protect against tonic hindlimb extension (THLE). Although CBD has been extensively studied, many other plant cannabinoids, including cannabigerol (CBG) and cannabichromene (CBC) previously have not been assessed for potential utility in epilepsy therapy.

Researchers at the University of California, Davis, have assessed cannabigerol (CBG)  and cannabichromene (CBC) for potential utility in epilepsy therapy. Utilizing a well-validated model to identify antiseizure agents, they have developed a method of treating or mitigating seizure, treating epilepsy, as well as a method of reducing the frequency of seizures via a therapeutically effective compound of formula.

Applications

  • Treating or mitigating convulsant effects 
  • Treating or mitigating seizures 
  • Treating or mitigating epilepsy

Features/Benefits

  • Reducing the frequency of seizures 
  • Potential to benefit large population of epilepsy patients

Patent Status

Country Type Number Dated Case
Patent Cooperation Treaty Published Application WO 2023/077146 05/04/2023 2022-512
 

Additional Patent Pending

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Inventors

  • Dhir, Ashish
  • Mascal, Mark J.
  • Rogawski, Michael A.

Other Information

Keywords

seizure, epilepsy, anticonvulsant, antiseizure medication, cannabigerol, cannabinoid

Categorized As