Microfluidic Bar Code Assay Device

Tech ID: 21847 / UC Case 2012-005-0

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 10,634,673 04/28/2020 2012-005
 

Brief Description

Current protein microarrays can analyze targets from a single sample against hundreds of surface-immobilized capture molecules. However, problems preventing widespread adoption of traditional protein microarrays include high costs, long assay times, or a lack of customization, sample multiplexing, and specificity.  

To meet these challenges, investigators at UC Berkeley have developed a rapid microfluidic device and assay using novel chemical and physical based techniques.  The microfluidic assay uses minimal sample volume (5μl) on a small footprint format, which is amendable to portable, low-cost and disposable use at the point-of-care.  The technology would allow the end user to rapidly pattern their own high-throughput arrays, reducing assay time from days or weeks to minutes.

 

Suggested uses

 

  • Clinical diagnostic devices and assays (e.g., identifying and detecting viral antibodies)
  • Protein testing (e.g., research and diagnostic applications)
  • Point-of-care diagnostic devices
  • Lab-on-a-chip microfluidic devices
  • Antibody development
  • Drug development and high-throughput pharmaceutical research

 

Advantages

  • Reduced consumption of sample and reagents
  • Portable, low-cost and disposable
  • Ease of automation
  • Fast reaction times

Publication

Microfluidic barcode assay for antibody based confirmatory diagnostics

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Inventors

  • Apori, Akwasi A.
  • Araz, Muhammet K.
  • Herr, Amy E.

Other Information

Keywords

Microfluidics, diagnostic, assay, electrophoresis, antibody detection, point-of-care, POC, confirmatory assay

Categorized As