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Automated Reconstruction Of The Cardiac Chambers From MRI

This is a fast, fully automated method to accurately model a patient’s left heart ventricle via machine learning algorithms.

A Process for Rapid, Continuous 3D Printing

Researchers at the University of California, Santa Barbara have developed a new method of continuous 3D printing that now allows complex, multiphase structures to be printed in a single process.

System and Method for High Density Assembly and Packaging of Micro-Reactors

High density micro-reactors are fabricated to form an array of wells into a surface for use in high throughput microfluidic applications in biology and chemistry. Researchers at the University of California, Irvine developed a method for increasing micro-reactor densities per unit area using rapidly self-assembled three-dimensional crystalline formation droplet arrays, and a device for performing the same.

Developing Physics-Based High-Resolution Head And Neck Biomechanical Models

UCLA researchers in the Department of Radiation Oncology at the David Geffen School of Medicine have developed a new computational method to model head and neck movements during medical imaging/treatment procedures.

Scanning Method For Uniform, Normal-Incidence Imaging Of Spherical Surface With A Single Beam

UCLA researchers have created a method that achieves uniform normal-incident illumination of a spherical surface by first projecting the sphere onto a Cartesian plane and then raster scanning it using an illuminating beam. This allows the scanned object, the illumination source, and the detector to remain stationary.

Estimation Of Contrast Concentration From Angiograms In Presence Of Vessel Overlap

UCLA researchers have developed an image processing technique for quantitative measurement of brain hemodynamics using x-ray digital subtraction angiography (DSA) images. 

Revolutionizing Micro-Array Technologies: A Microscopy Method and System Incorporating Nanofeatures

UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree incoherent holographic microscope using a plasmonic aperture.

Holographic Opto-Fluidic Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a system for holographic opto-fluidic microscopy.

Lensfree Super-Resolution Holographic Microscopy Using Wetting Films On A Chip

UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree super-resolution holographic microscope using wetting films on a chip.

Fluorescent Imaging Of Single Nano-Particles And Viruses On A Smart-Phone

UCLA researchers in the Department of Electrical Engineering have developed a novel field portable fluorescence microscope that can be used as a smart phone accessory.

Quantification Of Plant Chlorophyll Content Using Google Glass

UCLA researchers in the Department of Electrical Engineering have invented a novel device that can quantify chlorophyll concentration in plants using a custom-designed Google Glass app.

High-Throughput And Label-Free Single Nanoparticle Sizing Based On Time-Resolved On-Chip Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a rapid, low-cost, and label-free methodology for nanoparticle sizing.

Pixel Super-Resolution Using Wavelength Scanning

UCLA researchers have developed a novel way to significantly improve the resolution of an undersampled or pixelated image.

Microscopic Color Imaging And Calibration

UCLA researchers in the Department of Electrical Engineering have developed a color calibration method for lens-free and mobile-phone microscopy images allowing for high resolution and accurate color reproduction.

Wide-Field Imaging Of Birefringent Crystals In Synovial Fluid Using Lens-Free Polarized Microscopy For Crystal Arthropathy Diagnosis

UCLA researchers in the Department of Electrical Engineering have developed a new diagnostic tool for arthropathic diseases, such as gout.

Imaging Cells In Flow Cytometer Using Spatial-Temporal Transformation

Flow cytometry analyzes multiple physical characteristics of a large population of single cells as cells flow in a fluid stream through an excitation light beam. Flow cytometers measure fluorescence and light scattering from which information about the biological and physical properties of individual cells are obtained. Although flow cytometers have massive statistical power due to their single cell resolution and high throughput, they produce no information about cell morphology or spatial resolution offered by microscopy, which is a much wanted feature missing in almost all flow cytometers.

Measurement of Nanoscale Physical Enhancement by Materials under X-ray Irradiation

Researchers at the University of California, Davis have developed a method to study interactions of high density nanoparticles in solution with high spatial resolution.

Ultra-High Resolution Multi-Platform Heterodyne Optical Imaging

Researchers at the University of California, Davis have developed a new technique for achieving ultra-high resolution heterodyne synthetic imaging across multiple platforms (e.g. multiple satellites) using optical frequency comb sources.

Transabdominal Fetal Blood Oximetry

Researchers at the University of California, Davis have developed a method and apparatus for clinical-grade transabdominal fetal blood oximetry.

Genetically Encoded Fluorescent Sensors for Probing the Action of G-Protein Coupled Receptors (GPCRs)

Researchers at the University of California, Davis have developed a genetically encoded fluorescent sensor toolbox for the probing of G-protein coupled receptors.

Novel Applicator Using FTA Paper to Collect Touch DNA

Researchers at the University of California, Davis have developed a novel approach to an applicator designed to expedite and increase the efficiency of the DNA collection process at crime scenes.

Resolution Enhancement Method For Mm-Wave/Terahertz Imaging

UCLA researchers in the Department of Electrical Engineering have developed an imaging method based on low-cost CMOS process technologies showing enhanced resolution as high as 1.4THz.

Apparatus And Method For Optically Amplified Multi-Dimensional Spectrally Encoded Imaging

Scientists at UCLA have developed an advanced optical imaging technique that uses spectral brushes to capture image data across an entire sample area at once, a technique that enables faster imaging and higher sensitivity over current methods.

Novel Contrast Enhancement for Detection of Amyloid Beta Peptides using MRI, EPR, PET, and ESRM

Researchers at the University of California, Davis have developed nitroxide-coupled amyloid agents to produce contrast enhancement for amyloid beta peptide (Abeta) detection using MRI, EPR, PET, and ESRM.

Multiple in vivo tissue chromophores

The field of the invention generally relates to methods and devices used in diffuse optical spectroscopy. More specifically, the field of the invention generally relates to broadband diffuse optical spectroscopy methods and devices which are able to dynamically monitor multiple in vivo tissue chromophores. A device and method utilizes a broadband diffuse optical spectroscopy (DOS) system to dynamically calculate the concentrations of multiple chromophores in vivo using a non-invasive probe. The device and method permit dynamic monitoring of multiple in vivo tissue chromophores non-invasively with sensitivities necessary for effective therapeutic monitoring. The device includes a probe containing first and second source optical fibers as well as first and second detector optical fibers. The probe is placed adjacent to a sample of interest and detects reflected light which is passed to a proximally located detector and spectrometer. The concentrations of multiple chromophores are determined in real time. In a preferred embodiment, the multiple tissue chromophores include at least two of methemoglobin (MetHb), deoxyhemoglobin (Hb-R), oxyhemoglobin (Hb-O2), water (H2O), and methylene blue (MB). The device and method can be used quantify and monitor methemoglobin formation in subjects suffering from methemoglobinemia.

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