Soluble CD30 As A Surrogate Marker Of HIV-1 RNA

Tech ID: 34511 / UC Case 2022-237-0

Value Proposition

Antiretroviral therapy (ART) has substantially reduced the morbidity and mortality rates of HIV-1 infection, the persistence of viral reservoirs continues to prevent the elimination of HIV-1 from all tissue compartments. Consequently, there is still a need for point of care (POC) tests of circulating HIV levels (viral load) that do not rely on expensive technologies such as PCR.

Technology Description

UCSF Investigators have identified CD30, a stable, soluble protein as a surrogate biomarker for HIV-1 RNA, and are developing a POC assay for widespread distribution and use.

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Keywords

HIV-1, central nervous system, CNS, cerebrospinal fluid (CSF), CD30, point of care, viral reservoir, biomarker

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