Gene Targets For Manipulating T Cell Behavior
Tech ID: 33261 / UC Case 2020-043-0
Technology Description
By performing non-viral pooled knock-in screens, UCSF investigators have discovered novel genes that improve T cell functionality across a variety of in vitro assays. This invention includes novel compositions and methods for modifying the genome of a T cell to alter its specific and functionality, while limiting the side effects associated with T cell therapies.
Technology Advantages:
- Identifies novel gene targets
- Potential to enhance therapeutic potency of T cells for cancer and autoimmune applications
Patent Status
| Country | Type | Number | Dated | Case |
| United States Of America | Published Application | 20240392243 | 11/28/2024 | 2020-203 |
| Japan | Published Application | 2023-544161 | 11/30/2023 | 2020-203 |
Additional Patents Pending
Contact
- Gemma E. Rooney
- Gemma.Rooney@ucsf.edu
- tel: View Phone Number.
Other Information
Keywords
T cell therapy, Cancer, Immunotherapy