Anti-PSA IgG

Tech ID: 29782 / UC Case 2014-845-0


Researchers at UCLA have developed chimeric IgG specific for prostate-specific antigen (PSA) in human and mouse cells.


Prostate-specific antigen (PSA) is a substance made by cells in the prostate gland. Physicians use high PSA levels (above 4 nanograms per milliliter) as a blood biomarker for prostate cancer. Given this, a PSA antibody with high specificity to human PSA would benefit clinical diagnosis of prostate cancer.


Researchers at UCLA have developed a chimeric IgG specific antibody for the PSA in human and mouse cells. The variable regions of this antibody are those of the murine monoclonal antibody AR47.47. This novel antibody was expressed in murine myeloma cell lines, and is therefore cost efficient and easy to produce. It is properly assembled and secreted and binds PSA antigen


  • Detect levels of PSA in prostate cancer patients
  • Detect levels of PSA in experimental procedures performed in research laboratories


Specific to PSA

Developed in murine myeloma cell lines:

  • Cost-efficient
  • Easy to produce large quantities of antibody

State Of Development

Antibody has been developed and validated.


Learn About UC TechAlerts - Save Searches and receive new technology matches


  • Penichet, Manuel L.

Other Information


Antibody, prostate specific antigen, PSA, prostate cancer biomarker, diagnosis, diagnostic

Categorized As

Additional Technologies by these Inventors