Learn more about UC TechAlerts – Subscribe to categories and get notified of new UC technologies

Browse Category: Nanotechnology > NanoBio

Categories

[Search within category]

Anti-Microbial Contact Lens With Ocular Drug Delivery

Anti-microbial, anti-fungal drug eluting contact lens for the controlled release of ophthalmic therapeutics.

System and Method for High Density Assembly and Packaging of Micro-Reactors

High density micro-reactors are fabricated to form an array of wells into a surface for use in high throughput microfluidic applications in biology and chemistry. Researchers at the University of California, Irvine developed a method for increasing micro-reactor densities per unit area using rapidly self-assembled three-dimensional crystalline formation droplet arrays, and a device for performing the same.

Extracellular Nano-vesicles For Applications In Therapeutic Delivery

Drug delivery relies on nano-sized carriers whose objectives are to protect cargo from the body and to release the cargo at the appropriate site without inducing immunogenic response. The inventors at UCI have developed a method of mass producing extracellular nano-vesicles that have shown promise for drug delivery, but have been slow to progress to clinical trials due to low production yields.

Peripheral Nerve Repair By Peptide Amphiphile Nanofibers.

UCLA researchers in the Department of Surgery have developed a novel method that promotes directed nerve growth and peripheral nerve regeneration using peptide amphiphile (PA) nanofibers. The combination of conduit and PA nanofiber scaffold offers greater success than currently used methods of bridging with empty conduits. This novel approach may become a substitute for nerve graft for clinical use in the treatment of peripheral nerve injuries.

Microfluidics Device For Digestion Of Tissues Into Cellular Suspension

A microfluidic device that separates single cells from whole tissue in a rapid and gentle manner using hydrodynamic fluid flow. The separated single cell suspensions can then be used in tissue engineering applications, regenerative medicine and the study of cancer.

Holographic Opto-Fluidic Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a system for holographic opto-fluidic microscopy.

High-Throughput And Label-Free Single Nanoparticle Sizing Based On Time-Resolved On-Chip Microscopy

UCLA researchers in the Department of Electrical Engineering have developed a rapid, low-cost, and label-free methodology for nanoparticle sizing.

Rapid, Portable And Cost-Effective Yeast Cell Viability And Concentration Analysis Using Lensfree On-Chip Microscopy And Machine Learning

UCLA researchers in the Department of Electrical Engineering have developed a new portable device to rapidly measure yeast cell viability and concentration using a lab-on-chip design.

Process For Recycling Surfactant In Nanoemulsion Production

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method to separate and recycle surfactants used in the manufacturing of nanoemulsions.

Mechanical Process For Creating Particles Using Two Plates

UCLA researchers in the Department of Chemistry and Biochemistry & Physics and Astronomy have developed a novel method to lithograph two polished solid surfaces by using a simple mechanical alignment jig with piezoelectric control and a method of pressing them together and solidifying a material.

A General Method For Designing Self-Assembling Protein Nanomaterials

UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel computational method for designing proteins that self-assemble to a desired symmetric architecture. This method combines symmetrical docking with interface design, and it can be used to design a wide variety of self-assembling protein nanomaterials. 

Quantum Dot Incorporated Bacillus Spore As Nanosensor For Viral Detection

Researchers at UCLA and collaborating institutions have developed a simple and high-throughput method for preparing spore-based monodisperse microparticles (SMMs) from Bacillus subtilis. This new method enables them to form nanocomposites of CdTe quantum dot (QD)-loaded SMMs in a greener, more cost-effective manner.

Drop-Carrier Particles For Digital Assays

UCLA researchers in the Department of Bioengineering have developed a novel drop-carrier particle for single cell or single molecule assays.

Low Cost Wireless Spirometer Using Acoustic Modulation

The present invention relates to portable Spirometry system that uses sound to transmit pulmonary airflow information to a receiver.

Microfluidic Component Package

The present invention describes a component package that enables a microfluidic device to be fixed to a Printed Circuit Board (PCB) or other substrate, and embedded within a larger microfluidic system.

Method and System for Ultra High Dynamic Range Nucleic Acid Quantification

Researchers at UC Irvine developed a device and method that combines the high dynamic range and high accuracy of digital PCR (dPCR) with the real-time analysis of quantitative PCR (qPCR) to achieve a ultra-high dynamic range PCR over 10 to 12 orders of magnitude. The present method is accomplished by a highly integrated design that optimally packs, thermocycles, and images as many as 1 million reaction vessels.

Nanowire Building Block

Nanowires have applications as transistors or bioelectronic devices. Current methods to synthesize nanowires lack the ability to precisely control length, sequence, and terminal functionality. Using this invention as a building block, organic nanowires can be made with controlled length, sequence, and terminal functionality. The organic nanowires made with this invention also exhibit zero-resistance and do not degrade with increased length.

Soluble Fluorescent DNA Label

Assays or biosensors that utilize electrochemical or fluorescent techniques often employ DNA electrochemical probes. Current probes have drawbacks, as they have either electronic or fluorescent properties, are not readily water-soluble, and are poorly coupled within a DNA strand. This invention is a DNA electrochemical probe that has both electronic and fluorescent properties, is water-soluble, and can readily incorporate into a DNA strand.

Growth-Factor Nanocapsules With Tunable Release Capability For Bone Regeneration

UCLA researchers in the Departments of Chemical Engineering and Orthopedic Surgery have developed a method to deliver therapeutic proteins directly to the tumor site using nanocapsules.

High Performance and Flexible Chemical And Bio Sensors Using Metal Oxide Semiconductors

UCLA researchers in the Department of Materials Science and Engineering have developed a simple method producing thin, sensitive In2O3-based conformal biosensors based on field-effect transistors using facile solution-based processing for future wearable human technologies as well as non-invasive glucose testing.

Protein Nanocapsules With Detachable Zwitterionic Coating For Protein Delivery

UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a method to deliver therapeutic proteins directly to the tumor site using nanocapsules.

Evaporation-Based Method For Manufacturing And Recycling Of Metal Matrix Nanocomposites

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a new method to manufacture and recycle metal matrix nanocomposites.

New Method to Increase the Rate of Protein Ligation Catalyzed by the S. Aureus Sortase A Enzyme

UCLA researchers in the Department of Chemistry and Biochemistry have developed a new method to increase the rate of ligation catalyzed by the S. aureus Sortase A enzyme

PVA Nanocarrier System for Controlled Drug Delivery

Researchers at the University of California, Davis have designed and synthesized a unique type of water-soluble, biodegradable targeting poly(vinyl alcohol) (PVA) nanocarrier system for controlled delivery of boronic acid containing drugs, chemotherapy agents, proteins, photodynamic therapy agents and imaging agents.

Artificial cornea implant using nanopatterned synthetic polymer

The device is an artificial corneal implant comprised of a single, nanopatterned material. The device is durable, easy to implant, and robust against bacterial infection and other problems associated with other state-of-the-art ocular devices.

  • Go to Page: