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Programmable Peptide Nucleic Acid-Based Nanoplatform for Customizable Drug Delivery
Researchers at the University of California, Davis have developed a peptide nucleic acid-based system enabling precise and customizable delivery of antigens, adjuvants, and targeting molecules for improved cancer immunotherapy.
1-(Benzo[1,2-b:4,5-b']Difuran-4-yl)alkyl-2-amines and 1-(2,3,6,7-Tetrahydrobenzo[1,2-b:4,5-b']Difuran-4-yl)butan-2-amines as Serotonin Receptor Modulators for Neurodegenerative Disorders
Researchers at the University of California, Davis have developed novel serotonin receptor modulators designed as mixed 5-HT2A/2C partial agonists that demonstrate promising disease-modifying potential for Parkinson’s Disease with improved safety and efficacy.
Azocino[4,5,6-cd]Indoles, Methods for Preparation and Medical Use Thereof: Simplified Synthetic Access to a New Class of 5-HT Ligands
Researchers at the University of California, Davis have developed a novel class of compounds for modulating serotonin receptors, offering potential treatment for various psychiatric and neurological disorders without inducing hallucinogenic effects.
Flexor Tendon Imaging Apparatus
Researchers at the University of California, Davis have developed a portable apparatus that standardizes digit positioning and applies counter-resistance for improved imaging of the flexor tendon system in the hand.
Aluminum-mediated Base-free Catalysis for Transfer Hydrogenation
Researchers at the University of California, Davis have developed an aluminum catalyst that enables fast, base-free transfer hydrogenation of aldehydes and ketones using isopropanol as a hydrogen source.
Reusable, Sterilizable Surgical Instruments for Deployment of Neuropixels Probes in the Operating Room
Researchers at the University of California, Davis have developed a system of reusable, sterilizable 3D-printed surgical tools that enables safe, precise intraoperative deployment of Neuropixels probes within standard neurosurgical workflows.
Sealed Nanoreactors for X-Ray Dose Detection
Researchers at the University of California, Davis have developed a nanoreactor that allows for accurate measurements of radiation dose even in the vicinity of other chemicals.
Extruded Hydrogel Manufacturing Method for Adherent Cell Culture
Researchers at the University of California, Davis have developed a method for producing aligned, food-grade hydrogel fibers at high throughput for scalable cultivated meat manufacturing.