Tissue Orb - A Spherical Microfluidic Tissue Chip

Technology Description

The Tissue Orb is an innovative spherical microfluidic tissue chip designed to enhance the self-assembly of organoids into macroscopic, functional tissue structures. By providing a three-dimensional (3D) environment that eliminates physical biases and encourages uniform organoid distribution, this technology leverages cells’ natural ability to self-organize into complex tissues, including microvasculature, organ-specific parenchyma, and native extracellular matrix. The Tissue Orb features a central microporous conduit mimicking a blood vessel, enabling physiologic microfluidic flow to support tissue development. Currently at the proof-of-concept stage, this invention offers a novel approach to tissue engineering by optimizing organoid interaction dynamics in microgravity or microgravity analogs, setting it apart from other tissue culture systems.

Stage of Development

proof-of-concept

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Data Availability

Patent Status

Patent Pending