Broadband Optical Rotary Junction with High Return Loss for Analysis of Plaques

Abstract

Researchers at the University of California, Davis have developed an intravascular catheter system that integrates Fluorescence Lifetime Imaging (FLIm) with Polarization-Sensitive Optical Coherence Tomography (PS-OCT) for advanced plaque assessment in coronary artery disease.

Full Description

This intravascular catheter system merges the capabilities of FLIm and PS-OCT to offer a comprehensive multi-scale analysis of plaque structure and biochemical composition. It enables high-resolution morphological imaging, tissue microstructure analysis via polarimetry, and biochemical composition assessment without the need for any molecular contrast agents. The system is designed with a low profile and high-speed imaging capabilities, making it suitable for clinical research and diagnosis in cardiology.

Applications

• Advanced diagnostic tools for coronary artery disease. 
• Research tools in interventional cardiology for evaluating new treatment modalities. 
• Enhanced plaque characterization for the prevention of acute coronary syndromes.

Features/Benefits

• Possesses comprehensive multi-scale assessment of plaque features. 
• Enhances high-resolution imaging combined with biochemical composition analysis. 
• Introduces a low-profile catheter design suitable for percutaneous coronary intervention. 
• Mitigates cardiac motion artifacts with high-speed imaging capability. 
• Enables simultaneous acquisition of co-registered data across multiple spectral bands. 
• Broadens limited assessment capabilities compared to existing intravascular imaging technologies. 
• Enables simultaneously capturing detailed morphological and biochemical plaque features. 
• Does not require molecular contrast agents needed for traditional imaging modalities. 
• Paves the way for new treatment modalities for CAD.

Patent Status

Patent Pending