A Diagnostic And Extent Of Disease Multigene Assay For Thyroid Neoplasms

Tech ID: 33121 / UC Case 2006-092-0

Technology Description

The invention is a diagnostic assay for distinguishing benign from malignant thyroid neoplasms. The assay leverages a panel of differentially expressed biomarkers for diagnosis and to predict disease staging, with utility to complement FNA biopsy of thyroid nodules.

In studies (see below) the multigene assay correctly classified 93% of tumors into the correct risk group (low-risk versus high-risk), with a sensitivity of 78.9% (true positive in high-risk tumors) and specificity of 92% (true negative in low-risk tumors). Positive and negative predictive values were 87.5% and 92%, respectively. 

Looking for Partners

To commercialize the invention

Stage of Development

Preclinical

Related Materials

Data Availability

Available under CDA

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 7,901,888 03/08/2011 2006-092
 

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