This invention is a single-cell genotyping assay for direct measurement of the mutational damage present in individual human skin cells. The ability to detect somatic mutations in single skin cells eliminates “averaging” effects from bulk tissue sampling to enable genomic profiles of individual cells to be captured and quantified.
o Flag potentially pre-cancerous cells to
§Facilitate personalized screenings
§Enact prevention strategies to reduce risk of developing skin cancer
o Proactively implement lifestyle changes in advance of physical signs of skin aging
To commercialize the technology